rs1411224107, SERPINE1

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Miscarriage
CUI: C4552766
Disease: Miscarriage
0.010 GeneticVariation BEFREE Although factor XII C46T polymorphism is not associated with recurrent miscarriage (OR 1.07, 95% CI 0.52-2.22), factor XII deficiency is significantly associated (five studies, 1,096 women; OR 18.11, 95% CI 5.52-59.39), with minimal heterogeneity across studies. 17470597 2007
Factor XII Deficiency
CUI: C0015526
Disease: Factor XII Deficiency
0.010 GeneticVariation BEFREE Although factor XII C46T polymorphism is not associated with recurrent miscarriage (OR 1.07, 95% CI 0.52-2.22), factor XII deficiency is significantly associated (five studies, 1,096 women; OR 18.11, 95% CI 5.52-59.39), with minimal heterogeneity across studies. 17470597 2007
Arteriosclerosis Obliterans
CUI: C0003851
Disease: Arteriosclerosis Obliterans
0.010 GeneticVariation BEFREE The present paper reports the association of the 46C/T polymorphism with plasma XIIa levels in apparently healthy subjects, and in patients with ischemic cerebrovascular disease (CVD) and arteriosclerosis obliterans (ASO). 10870808 2000
Cerebrovascular Disorders
CUI: C0007820
Disease: Cerebrovascular Disorders
0.010 GeneticVariation BEFREE The present paper reports the association of the 46C/T polymorphism with plasma XIIa levels in apparently healthy subjects, and in patients with ischemic cerebrovascular disease (CVD) and arteriosclerosis obliterans (ASO). 10870808 2000