rs1419881, TCF19

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.800 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.800 GeneticVariation GWASCAT A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
Hepatitis B, Chronic
CUI: C0524909
Disease: Hepatitis B, Chronic
0.700 GeneticVariation GWASCAT Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B. 25802187 2015
Complete atrioventricular block
CUI: C0151517
Disease: Complete atrioventricular block
0.020 GeneticVariation BEFREE In our previous GWAS, TCF19 was identified as one of the susceptibility genes for CHB risk (P=4.2×10<sup>-9</sup> at rs1419881). 27596359 2017
Complete atrioventricular block
CUI: C0151517
Disease: Complete atrioventricular block
0.020 GeneticVariation BEFREE This study identified two new risk-associated loci for CHB on the HLA region of chromosome 6, e.g. rs652888 on euchromatic histone-lysine-methyltransferase 2 (EHMT2, P = 7.07 × 10(-13)) and rs1419881 on transcription factor 19 (TCF19, P = 1.26 × 10(-18)). 23760081 2013
Multiple Myeloma
CUI: C0026764
Disease: Multiple Myeloma
0.010 GeneticVariation BEFREE The SNPs rs13409 (located in the 3'UTR of the POU5F1 gene), rs1419881 (TCF19), rs1049633, rs1049623 (both in DDR1) showed significant associations with MM risk. 27718532 2017