rs143894582, PTPN11

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
response to alcohol
CUI: C3548532
Disease: response to alcohol
0.700 GeneticVariation GWASCAT Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population. 29460428 2018
Flushing
CUI: C0016382
Disease: Flushing
0.010 GeneticVariation BEFREE All 3 traits showed genomewide significant association with variants near ALDH2, with significance ranging from 2.01 × 10<sup>-14</sup> (for flushing; lead single nucleotide polymorphism (SNP) PTPN11* rs143894582) to p<sub>meta</sub>  = 5.80 × 10<sup>-10</sup> (for alcohol dependence criterion count; lead SNP rs149212747). 29460428 2018
Alcoholic Intoxication, Chronic
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
0.010 GeneticVariation BEFREE All 3 traits showed genomewide significant association with variants near ALDH2, with significance ranging from 2.01 × 10<sup>-14</sup> (for flushing; lead single nucleotide polymorphism (SNP) PTPN11* rs143894582) to p<sub>meta</sub>  = 5.80 × 10<sup>-10</sup> (for alcohol dependence criterion count; lead SNP rs149212747). 29460428 2018