rs1495741, None

N. diseases: 9
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. 30926973 2019
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422 2018
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASDB Discovery and refinement of loci associated with lipid levels. 24097068 2013
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASCAT Discovery and refinement of loci associated with lipid levels. 24097068 2013
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASDB Discovery and refinement of loci associated with lipid levels. 24097068 2013
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT Discovery and refinement of loci associated with lipid levels. 24097068 2013
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.800 GeneticVariation GWASCAT Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASCAT Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Triglycerides measurement
CUI: C0202236
Disease: Triglycerides measurement
0.800 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.720 GeneticVariation BEFREE To quantify the association between rs1495741 and the risk of bladder cancer and to estimate the interaction effect of this genetic variant with smoking, we performed a systematic literature review and meta-analysis involving 14,815 cases and 58,282 controls from 29 studies. 27495060 2016
Malignant neoplasm of urinary bladder
0.720 GeneticVariation BEFREE To quantify the association between rs1495741 and the risk of bladder cancer and to estimate the interaction effect of this genetic variant with smoking, we performed a systematic literature review and meta-analysis involving 14,815 cases and 58,282 controls from 29 studies. 27495060 2016
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.720 GeneticVariation GWASCAT Genome-wide association study identifies multiple loci associated with bladder cancer risk. 24163127 2014
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.720 GeneticVariation BEFREE Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at </span>8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65. 24740636 2014
Malignant neoplasm of urinary bladder
0.720 GeneticVariation BEFREE Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at </span>8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65. 24740636 2014
Malignant neoplasm of urinary bladder
0.720 GeneticVariation GWASDB Genome-wide association study identifies multiple loci associated with bladder cancer risk. 24163127 2014
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.720 GeneticVariation GWASCAT A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. 20972438 2010
Malignant neoplasm of urinary bladder
0.720 GeneticVariation GWASDB A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. 20972438 2010
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.710 GeneticVariation GWASCAT Genomewide Association Study Confirming the Association of NAT2 with Susceptibility to Antituberculosis Drug-Induced Liver Injury in Thai Patients. 31109976 2019
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.710 GeneticVariation BEFREE The aim of this report was to evaluate the level of agreement and accuracy of two recently recommended markers, the two-single nucleotide polymorphisms (SNP) (C282T and T341C) and tagSNP of NAT2 (rs1495741) genotypes, to predict the seven-SNP-inferred NAT2 phenotype in Bolivian and Argentinian tuberculosis (TB)-patient populations. 27104815 2016
Chemical and Drug Induced Liver Injury
0.700 GeneticVariation GWASCAT Genomewide Association Study Confirming the Association of NAT2 with Susceptibility to Antituberculosis Drug-Induced Liver Injury in Thai Patients. 31109976 2019
Drug-Induced Liver Disease
CUI: C0860207
Disease: Drug-Induced Liver Disease
0.030 GeneticVariation BEFREE Two SNPs in NAT2 (rs1041983 and rs1495741) and NAT2 slow acetylators (SA) were significantly associated with INH-DILI (OR (95% CI) = 13.86 (4.30-44.70), 0.10 (0.03-0.33) and 9.98 (3.32-33.80), respectively). 29036176 2017
Drug-Induced Liver Disease
CUI: C0860207
Disease: Drug-Induced Liver Disease
0.030 GeneticVariation BEFREE tagSNP rs1495741 as a useful molecular marker to predict antituberculosis drug-induced hepatotoxicity. 27104815 2016
Drug-Induced Liver Disease
CUI: C0860207
Disease: Drug-Induced Liver Disease
0.030 GeneticVariation BEFREE The NAT2 tag SNP rs1495741 correlates with the susceptibility of antituberculosis drug-induced hepatotoxicity. 23407048 2013