rs1518111, IL19;IL10

N. diseases: 9
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Behcet Syndrome
CUI: C0004943
Disease: Behcet Syndrome
0.830 GeneticVariation BEFREE Interestingly, we have found, majority of the tribal populations have low frequency of VL ('A' of rs3024498); and high frequency of leprosy ('T' of rs1554286), and Behcet's ('A' of rs1518111) associated alleles, whereas these were vice versa in castes. 25941808 2015
Behcet Syndrome
CUI: C0004943
Disease: Behcet Syndrome
0.830 GeneticVariation BEFREE Similarly, rs1518111, which showed strong linkage disequilibrium (r(2)=1) with allele rs1800871, was also associated with BD (pc=0.026). 24269690 2014
Behcet Syndrome
CUI: C0004943
Disease: Behcet Syndrome
0.830 GeneticVariation BEFREE In IL10, rs1518111 was nominally associated with BD before and after adjustment for population stratification (odds ratio [OR] for T allele 1.20, 95% confidence interval [95% CI] 1.02-1.40, unadjusted P [P(unadj) ] = 2.53 × 10(-2) ; adjusted P [P(adj) ] = 1.43 × 10(-2) ), and rs1554286 demonstrated a trend toward association (P(unadj) = 6.14 × 10(-2) ; P(adj) = 3.21 × 10(-2) ). 22378604 2012
Behcet Syndrome
CUI: C0004943
Disease: Behcet Syndrome
0.830 GeneticVariation GWASDB Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878 2010
Behcet Syndrome
CUI: C0004943
Disease: Behcet Syndrome
0.830 GeneticVariation GWASCAT Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. 20622878 2010
Lupus Erythematosus
CUI: C0409974
Disease: Lupus Erythematosus
0.010 GeneticVariation BEFREE Meanwhile, significant difference in genotype frequency at rs1518110 and rs1518111 were found in patients with and without lupus headache (P=0.025, P=0.038, respectively). 29199038 2018
Lupus Vulgaris
CUI: C0024131
Disease: Lupus Vulgaris
0.010 GeneticVariation BEFREE Meanwhile, significant difference in genotype frequency at rs1518110 and rs1518111 were found in patients with and without lupus headache (P=0.025, P=0.038, respectively). 29199038 2018
Tuberculosis, Pulmonary
CUI: C0041327
Disease: Tuberculosis, Pulmonary
0.010 GeneticVariation BEFREE We found correlations between one SNP in IL6 (rs2069837 <i>p</i> = 6.63E-11), seven SNPs in <i>IL10</i> (rs1554286 <i>p</i> = 6.87E-20, rs1518111 <i>p</i> = 6.11E-11, rs3021094 <i>p</i> = 6.75E-29, rs3790622 <i>p</i> = 2.40E-06, rs3024490 <i>p</i> = 6.73E-11, rs1800872 <i>p</i> = 6.18E-11, rs1800871 <i>p</i> = 6.73E-11) and incidences of PTB. 29662655 2018
Lupus Erythematosus, Discoid
CUI: C0024138
Disease: Lupus Erythematosus, Discoid
0.010 GeneticVariation BEFREE Meanwhile, significant difference in genotype frequency at rs1518110 and rs1518111 were found in patients with and without lupus headache (P=0.025, P=0.038, respectively). 29199038 2018
Headache
CUI: C0018681
Disease: Headache
0.010 GeneticVariation BEFREE Meanwhile, significant difference in genotype frequency at rs1518110 and rs1518111 were found in patients with and without lupus headache (P=0.025, P=0.038, respectively). 29199038 2018
Lupus Erythematosus, Systemic
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
0.010 GeneticVariation BEFREE Meanwhile, significant difference in genotype frequency at rs1518110 and rs1518111 were found in patients with and without lupus headache (P=0.025, P=0.038, respectively). 29199038 2018
Mycobacterium Infections
CUI: C0026918
Disease: Mycobacterium Infections
0.010 GeneticVariation BEFREE Susceptibility to non-tuberculous mycobacterial disease is influenced by rs1518111 in IL10. 28174026 2017
Leishmaniasis, Visceral
CUI: C0023290
Disease: Leishmaniasis, Visceral
0.010 GeneticVariation BEFREE Interestingly, we have found, majority of the tribal populations have low frequency of VL ('A' of rs3024498); and high frequency of leprosy ('T' of rs1554286), and Behcet's ('A' of rs1518111) associated alleles, whereas these were vice versa in castes. 25941808 2015