rs1552224, ARAP1

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation BEFREE In the first stage, SNPs rs1552224 at CENTD2 were significantly associated with T2D and the association was statistically significant in the whole study population (P = 0.001) although it was not replicated in the second stage. rs1552224 and rs2237897 of KCNQ1 showed significant joint effect on T2D and there was a significant decreased risk of T2D with the number increase of risk alleles (P for trend = 3.81 × 10(-17)). 25749274 2015
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASDB Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation BEFREE Variants of SNPs rs7903146, rs1552224 and rs11642841 in the control group and rs7903146 in T2DM group showed significant association with both BMI and WC. 24435973 2014
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASDB Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals. 21647700 2011
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASCAT Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. 20581827 2010
Diabetes Mellitus, Non-Insulin-Dependent
0.820 GeneticVariation GWASDB Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. 20581827 2010
Fasting blood sugar result
CUI: C1261430
Disease: Fasting blood sugar result
0.700 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
Fasting blood glucose measurement
CUI: C0428568
Disease: Fasting blood glucose measurement
0.700 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922 2012
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.010 GeneticVariation BEFREE We discovered that GDM was associated with rs945508 (OR = 1.368, 95% CI = 1.080-1.732, p = .009), rs10804591 (OR = 1.446, 95% CI = 1.192-1.754, p < .001), rs10245353 (OR = 1.204, 95% CI = 1.006-1.441, p = .043) and rs1552224 (OR = 1.451, 95% CI = 1.071-1.964, p = .016). 28554271 2018