rs157590, TOMM40

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.700 GeneticVariation GWASDB SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. 23565137 2013
Primary Progressive Aphasia (disorder)
CUI: C0282513
Disease: Primary Progressive Aphasia (disorder)
0.010 GeneticVariation BEFREE Inside this region of 16.3 kb, LD (r2 = 0.14) between TOMM40 (rs157590) and APOE (rs429358) was observed in PPA, but not in bvFTD and in controls. 22710912 2012
Behavioral variant of frontotemporal dementia
CUI: C4011788
Disease: Behavioral variant of frontotemporal dementia
0.010 GeneticVariation BEFREE Inside this region of 16.3 kb, LD (r2 = 0.14) between TOMM40 (rs157590) and APOE (rs429358) was observed in PPA, but not in bvFTD and in controls. 22710912 2012