Diffuse Large B-Cell Lymphoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Genotyping for C1qA[276A/G] was done in 164 patients with DLBCL.
|
22897949 |
2012 |
Diffuse Large B-Cell Lymphoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
The influence of C1qA-A276G polymorphisms in DLBCL, and the impact of both polymorphisms on susceptibility to LON and outcome were also examined.
|
21883784 |
2012 |
Neoplasm Metastasis
|
|
0.020 |
GeneticVariation
|
BEFREE |
A synonymous single nucleotide polymorphism (SNP) rs172378 (A>G, Gly->Gly) in the complement component C1QA has been proposed to be associated with distant breast cancer metastasis.
|
20332777 |
2010 |
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found that although rs172378 showed differential allelic expression significantly different between normal (preferentially expressing the G allele) and tumour tissue samples (preferentially expressing the A allele), there was no significant difference in survival by rs172378 genotype (per allele hazard ratio (HR) 1.02, 95% CI: 0.88-1.19, P=0.78 for all-cause mortality; HR 1.03, 95% CI: 0.87-1.22, P=0.72 for breast-cancer-specific mortality).
|
20332777 |
2010 |
Breast Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our study results show that rs172378 is linked to a cis-regulatory element affecting gene expression and that allelic preferential expression is altered in tumour samples, but do not support an association between genetic variation in C1QA and breast cancer survival.
|
20332777 |
2010 |
Malignant neoplasm of breast
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our study results show that rs172378 is linked to a cis-regulatory element affecting gene expression and that allelic preferential expression is altered in tumour samples, but do not support an association between genetic variation in C1QA and breast cancer survival.
|
20332777 |
2010 |
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Genotyping for C1qA[276A/G] was performed in 63 breast cancer subjects with localized tumor and compared with that in 38 breast cancer subjects with metastasis.
|
16465510 |
2006 |
Neoplasm Metastasis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Genotyping for C1qA[276A/G] was performed in 63 breast cancer subjects with localized tumor and compared with that in 38 breast cancer subjects with metastasis.
|
16465510 |
2006 |
Malignant neoplasm of breast
|
|
0.020 |
GeneticVariation
|
BEFREE |
There was no statistical difference in the C1qA[276A/G] allelic distribution between all subjects with breast cancer and controls.
|
16465510 |
2006 |
Breast Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
There was no statistical difference in the C1qA[276A/G] allelic distribution between all subjects with breast cancer and controls.
|
16465510 |
2006 |
Lupus Nephritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
These results support the implication of the G allele in rs172378 as a risk factor for lupus nephritis in a homozygous status, at least for a Bulgarian population.
|
25326229 |
2015 |
Late onset neutropenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The FCGR3A-V158F but not the C1qA-A276G polymorphism influenced the risk of developing LON.
|
21883784 |
2012 |
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
The C1qA SNPs, rs172378 and rs665691, confer no genetic predisposition to SLE in a Chinese Han population.
|
22236909 |
2012 |
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
We analysed the gene expression pattern of rs172378 in normal and tumour tissue samples, and further explored its involvement in relation to mortality in 2270 women with breast cancer participating in Studies of Epidemiology and Risk factors in Cancer Heredity, a population-based case-control study.
|
20332777 |
2010 |
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
We analysed the gene expression pattern of rs172378 in normal and tumour tissue samples, and further explored its involvement in relation to mortality in 2270 women with breast cancer participating in Studies of Epidemiology and Risk factors in Cancer Heredity, a population-based case-control study.
|
20332777 |
2010 |
Lymphoma, Follicular
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genotyping for C1qA([276A/G]) was done in 133 subjects with follicular lymphoma treated with single-agent rituximab, and correlation with clinical response was done using Cox regression analysis.
|
18927313 |
2008 |