rs1761667, CD36

N. diseases: 12
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE The present findings revealed an association between CD36 rs1761667 polymorphism and susceptibility to hypertension and/or CAD in a southeastern Iranian population. 31185924 2019
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE Our results suggested that the AA genotype of rs1761667 in the CD36 gene was associated with higher intake of total fat and MUFA and lower risk of hypertension in a Japanese population. 30924431 2019
Obesity
CUI: C0028754
Disease: Obesity
0.030 GeneticVariation BEFREE We determined whether single nucleotide polymorphisms (SNPs; rs1761667 and rs1527483) in the fatty acid translocase CD36 gene - a receptor for fatty acids - is associated with oral fat perception (OFP) of different fat contents in custards and commercially-available foods, and obesity measures in Malaysian subjects (n=313; 118 males, 293 ethnic Chinese; 20 ethnic Indians). 27847178 2017
Obesity
CUI: C0028754
Disease: Obesity
0.030 GeneticVariation BEFREE A significant genetic association between CD36 genotype and fat intake was observed for the A allele of rs1761667, which was associated with a decreased intake of total fat (g/day) (p = 0.01), polyunsaturated and monounsaturated fatty acids (% kcal and g/day), total sugars (g/day) (p = 0.01), fatty foods (portion and g/day) (p < 0.001 for both), and vegetable oils (mL/day) (p = 0.02) only in obese subjects. 28237985 2016
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE The association of CD36 SNP rs1761667 with body mass index (BMI) and hypertension was therefore studied in a Finnish cohort of adults. 25723554 2015
Obesity
CUI: C0028754
Disease: Obesity
0.030 GeneticVariation BEFREE We also studied the association between rs1761667 polymorphism of CD36 gene and obesity. 26556365 2015
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.010 GeneticVariation BEFREE CD36 gene polymorphism rs1761667 (G > A) is associated with hypertension and coronary artery disease in an Iranian population. 31185924 2019
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.010 GeneticVariation BEFREE The present findings revealed an association between CD36 rs1761667 polymorphism and susceptibility to hypertension and/or CAD in a southeastern Iranian population. 31185924 2019
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.010 GeneticVariation BEFREE CD36 gene polymorphism rs1761667 (G > A) is associated with hypertension and coronary artery disease in an Iranian population. 31185924 2019
FAMILIAL ADENOMATOUS POLYPOSIS, ATTENUATED (disorder)
0.010 GeneticVariation BEFREE The results revealed a substantially lower age of polyposis diagnosis for patients belonging to the severe FAP group (harbouring <i>adenomatous polyposis coli (APC)</i> variants in the mutation cluster region (MCR)) and high age for patients in the attenuated familial adenomatous polyposis (AFAP) group for SNPs rs1761667 and rs1984112. 30065793 2018
Taste sweet
CUI: C0858600
Disease: Taste sweet
0.010 GeneticVariation BEFREE The rs1761667 single nucleotide polymorphism (SNP) in the <i>CD36</i> gene has been linked to fat taste sensitivity, the rs35874116 SNP in the <i>TAS1R2</i> gene has been related to sweet taste preference, and the rs713598 SNP in the <i>TAS2R38</i> gene has been associated with aversion to bitter, green leafy vegetables. 29385734 2018
Adenomatous Polyposis Coli
CUI: C0032580
Disease: Adenomatous Polyposis Coli
0.010 GeneticVariation BEFREE The results revealed a substantially lower age of polyposis diagnosis for patients belonging to the severe FAP group (harbouring <i>adenomatous polyposis coli (APC)</i> variants in the mutation cluster region (MCR)) and high age for patients in the attenuated familial adenomatous polyposis (AFAP) group for SNPs rs1761667 and rs1984112. 30065793 2018
Intraocular pressure disorder
CUI: C0595921
Disease: Intraocular pressure disorder
0.010 GeneticVariation BEFREE Three polymorphisms were found to be associated with increases in IOP: rs1049673 (p = 0.006), rs3211931 (p = 0.01), and rs1761667 (p = 0.043) at the time of the third injection only. 28557591 2018
Multiple polyps
CUI: C0334108
Disease: Multiple polyps
0.010 GeneticVariation BEFREE The results revealed a substantially lower age of polyposis diagnosis for patients belonging to the severe FAP group (harbouring <i>adenomatous polyposis coli (APC)</i> variants in the mutation cluster region (MCR)) and high age for patients in the attenuated familial adenomatous polyposis (AFAP) group for SNPs rs1761667 and rs1984112. 30065793 2018
Carotid Atherosclerosis
CUI: C0577631
Disease: Carotid Atherosclerosis
0.010 GeneticVariation BEFREE The presence of rs1761667 GA and rs12998782 CT may increase the risk for carotid atherosclerosis among postmenopausal females. 28866086 2017
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.010 GeneticVariation BEFREE Our findings show that CD36 rs1761667 SNP is positively associated with increased risk of MetS and its components with genotype AG heterozygotes showing highest frequency among MetS patients. 22588808 2012