|
Malignant neoplasm of esophagus
|
|
0.020 |
GeneticVariation
|
BEFREE |
The purpose of the present study was to investigate the polymorphisms of -938C/A, Thr43Ala in anti-apoptotic B-cell lymphoma 2 gene (BCL2) and -248G/A in pro-apoptotic B-cell lymphoma 2-associated X protein gene (BAX) and to explore their role in influencing the susceptibility for development of esophageal cancer.
|
22187149 |
2012 |
|
Esophageal carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
The purpose of the present study was to investigate the polymorphisms of -938C/A, Thr43Ala in anti-apoptotic B-cell lymphoma 2 gene (BCL2) and -248G/A in pro-apoptotic B-cell lymphoma 2-associated X protein gene (BAX) and to explore their role in influencing the susceptibility for development of esophageal cancer.
|
22187149 |
2012 |
|
Esophageal Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
The purpose of the present study was to investigate the polymorphisms of -938C/A, Thr43Ala in anti-apoptotic B-cell lymphoma 2 gene (BCL2) and -248G/A in pro-apoptotic B-cell lymphoma 2-associated X protein gene (BAX) and to explore their role in influencing the susceptibility for development of esophageal cancer.
|
22187149 |
2012 |
|
Esophageal carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer.
|
17561354 |
2007 |
|
Malignant neoplasm of esophagus
|
|
0.020 |
GeneticVariation
|
BEFREE |
Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer.
|
17561354 |
2007 |
|
Esophageal Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer.
|
17561354 |
2007 |
|
Fetal Alcohol Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
Genotyping of BCL2 (ala43thr), FAS (A-670G), CCND1 (G870A), EGF (+61A/G) and EGFR (G497A) polymorphisms were determined using the polymerase chain reaction followed by restriction fragment length polymorphism methodology.
|
17912028 |
2007 |
|
Fetal Alcohol Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer.
|
17561354 |
2007 |
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Bcl-2 rs1800477A/G polymorphism may be related to the occurrence of CRC, and GG genotype could be a risk factor of poor prognosis in CRC.
|
28106544 |
2017 |
|
Secondary malignant neoplasm of lymph node
|
|
0.010 |
GeneticVariation
|
BEFREE |
The GG genotype of rs1800477A/G was associated with lymph node metastasis and Dukes' staging of CRC (both P < 0.05).
|
28106544 |
2017 |
|
Lymphoma, Non-Hodgkin
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to investigate whether polymorphisms of - 938C/A and Thr43Ala in the BCL-2 gene and G - 248A in the BAX gene are associated with the risk of developing non-Hodgkin lymphoma (NHL).
|
24024471 |
2014 |
|
B-Cell Lymphomas
|
|
0.010 |
GeneticVariation
|
BEFREE |
The purpose of the present study was to investigate the polymorphisms of -938C/A, Thr43Ala in anti-apoptotic B-cell lymphoma 2 gene (BCL2) and -248G/A in pro-apoptotic B-cell lymphoma 2-associated X protein gene (BAX) and to explore their role in influencing the susceptibility for development of esophageal cancer.
|
22187149 |
2012 |
|
Hepatitis C
|
|
0.010 |
GeneticVariation
|
BEFREE |
Quantification of HCV-RNA by real-time PCR was performed for every patient, and gene polymorphism of BCL-2 (ala 43 Thr) was performed for all patients and controls.
|
21159314 |
2011 |
|
Virus Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
BCL-2 gene polymorphism at codon 43 (127G/A) has been found to be a reliable and sensitive marker for the prediction of response to interferon therapy during viral infections.
|
21159314 |
2011 |
|
Azoospermia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Considering the decreased antiapoptotic function of BCL2, these results suggest that the Ala43Thr variant is associated with protection against azoospermia in the Han-Chinese population.
|
20610805 |
2010 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
In contrast to what was observed in Japanese diabetic/control individuals, we find no evidence for association of the BCL2 Ala43Thr polymorphism to T1DM in Danish, Finnish and Basque Type 1 diabetes families.
|
11704806 |
2001 |