|
Acute appendicitis NOS (disorder)
|
|
0.010 |
GeneticVariation
|
BEFREE |
With this study we investigated the contribution of IL-6 (-572G/C rs1800796) and IL-6R (1:G.154448302 T > C rs7529229) polymorphisms on pathogenesis, and severity of AA in pediatric patients with AA: These results will guide further genetic researches to be performed on the role of IL-6 and IL-6R in AA.
|
26714766 |
2015 |
|
Acute Chest Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
the results suggest that IL-6 -572 G>C (rs1800796) polymorphism could be involved in the risk of developing ACS in Mexican individuals.
|
20939703 |
2010 |
|
Acute Coronary Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The interleukin 6 -572 G>C (rs1800796) polymorphism is associated with the risk of developing acute coronary syndrome.
|
20939703 |
2010 |
|
Acute pancreatitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, there were no significant associations between IL-1β (IL-1β +3954 C/T (rs1143634) and IL-1β -511 C/T (rs16944)), IL-6 (IL-6 -174 G/C (rs1800795) and IL-6 -634 C/G (rs1800796)) and IL-10 (IL-10 -1082 A/G (rs1800896), IL-10 -819 C/T (rs1800871) and IL-10 -592 C/A (rs1800872)) gene polymorphisms and AP risk.
|
24072654 |
2013 |
|
Allergic rhinitis (disorder)
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to investigate the role played by the IL-6 rs1800795 (-174G/C) and rs1800796 (-572G>C) polymorphisms in the susceptibility to allergic rhinitis in a Chinese population.
|
26909898 |
2016 |
|
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
|
|
0.010 |
GeneticVariation
|
BEFREE |
Here we investigated the prognostic value and association of SELP-rs6136, IL6-rs1800796 and AKT1-rs1130233 polymorphisms with cachexia in PDAC.
|
25238546 |
2014 |
|
Appendicitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
With this study we investigated the contribution of IL-6 (-572G/C rs1800796) and IL-6R (1:G.154448302 T > C rs7529229) polymorphisms on pathogenesis, and severity of AA in pediatric patients with AA: These results will guide further genetic researches to be performed on the role of IL-6 and IL-6R in AA.
|
26714766 |
2015 |
|
Breast Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results suggest that the contribution of diabetes to breast cancer risk might be modified by IL-6 rs1800796 and HSPD1 rs2605039.
|
28591216 |
2017 |
|
Breast Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
IL6 genotype and haplotype significantly modified the association between aspirin and breast cancer, with the greatest effect modification being among women not recently exposed to hormones [P interaction = 0.06 (for non-Hispanic white) and 0.04 (for Hispanic/Native American) and SNP rs1800796 or -572G>C].
|
17416766 |
2007 |
|
Cachexia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association of SELP-rs6136, IL6-rs1800796 and AKT1-rs1130233 polymorphisms with cachexia as well as the correlation between cachexia and the candidate polymorphisms and overall survival were analyzed.
|
25238546 |
2014 |
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The present meta-analysis suggested that there was no association between IL-6 rs1800796 polymorphism and lung cancer, which was independent of smoking status.
|
24984610 |
2014 |
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
Overall, the cross-validation consistency of this model was 10/10, and the testing accuracy was 62.17%, and participants with rs1800805-GA or AA and rs1800796-GC or CC genotype have the highest CVD risk, compared to participants with rs1800805-GG and rs1800796-GG genotypes, and OR (95% CI) was 2.52 (1.81-2.66).
|
28819827 |
2017 |
|
Celiac Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to investigate polymorphisms in the genes responsible for encoding cytokines interleukin-6 (IL-6) (-572G/C) (rs1800796) and IL-17 (-197A/G) (rs2275913) in patients with celiac disease (CD).
|
28928101 |
2017 |
|
Cerebral arterial thrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We conducted a case-control study to investigate the influence of IL6 -174G/C (rs1800795) and -572C/G (rs1800796) genetic variants on the development of cerebral thrombosis in a Chinese population.
|
26662441 |
2015 |
|
Cerebral Palsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
Cerebral Thrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We conducted a case-control study to investigate the influence of IL6 -174G/C (rs1800795) and -572C/G (rs1800796) genetic variants on the development of cerebral thrombosis in a Chinese population.
|
26662441 |
2015 |
|
Childhood asthma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In recent years, cytokines and their receptors have been shown to be highly polymorphic, and this prompted us to investigate interleukin 6 promoter polymorphisms at position -174G/C (rs1800795) and at -572G/C (rs1800796) in relation to asthma in children.
|
28185773 |
2017 |
|
Chorioamnionitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis.
|
30795743 |
2019 |
|
Chronic Periodontitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
G/G genotype of IL-6 rs1800796 appears to be associated with an increased risk of chronic periodontitis.
|
30300034 |
2019 |
|
Colorectal Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |
|
Colorectal Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Data from a multi-center case-control study of colon (N = 1579 cases and N = 1977 controls) and rectal (N = 794 cases and N = 1005 controls) cancer were used to evaluate the association between the rs1800795 and rs1800796 IL6 polymorphisms and CRC.
|
17694420 |
2007 |
|
Cone-Rod Dystrophy 2
|
|
0.010 |
GeneticVariation
|
BEFREE |
The GG genotype of rs1800796 predisposes to sepsis in CRD and to 28-day mortality by sepsis-unrelated cardiovascular phenomena.
|
26463449 |
2015 |
|
Congenital Dysplasia Of The Hip
|
|
0.020 |
GeneticVariation
|
BEFREE |
Data suggest association between TGFB1 29 T → C transition (rs1800470) and IL6 -572G → C transversion (rs1800796) with DDH, and also a possibility of TGF-beta1 and IL-6 interaction in DDH pathogenesis.
|
25603974 |
2015 |