|
Tuberculosis
|
|
0.020 |
GeneticVariation
|
BEFREE |
rs1800796 of the IL6 gene is associated with increased risk for anti-tuberculosis drug-induced hepatotoxicity in Chinese Han children.
|
30029918 |
2018 |
|
Drug-Induced Liver Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
rs1800796 of the IL6 gene is associated with increased risk for anti-tuberculosis drug-induced hepatotoxicity in Chinese Han children.
|
30029918 |
2018 |
|
Osteoporosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
After adjusting for age, the IL6 -634G > C (rs1800796) allele showed association with osteoporosis (odds ratio (OR) for CC + CG = 2.51, p = 0.0047)), independent of statin use or smoking status.
|
19506792 |
2010 |
|
Chorioamnionitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of a placental Interleukin-6 genetic variant (rs1800796) with DNA methylation, gene expression and risk of acute chorioamnionitis.
|
30795743 |
2019 |
|
Degenerative polyarthritis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Association of interleukin-6 gene polymorphism (rs1800796) with severity and functional status of osteoarthritis in elderly individuals.
|
26233477 |
2015 |
|
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation
|
BEFREE |
Considering these promising results, IL-6 promoter including rs1800795, rs1800796 and rs1800797 may be a tumor marker for cancer therapy.
|
29552316 |
2018 |
|
Malignant Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
Considering these promising results, IL-6 promoter including rs1800795, rs1800796 and rs1800797 may be a tumor marker for cancer therapy.
|
29552316 |
2018 |
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
CRP rs2794520 (OR=1.64, 95% CI=1.19-2.26) and IL6 rs1800796 (OR=1.41, 95% CI=1.02-1.96) were associated with lung cancer risk.
|
24139238 |
2014 |
|
Colorectal Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Data from a multi-center case-control study of colon (N = 1579 cases and N = 1977 controls) and rectal (N = 794 cases and N = 1005 controls) cancer were used to evaluate the association between the rs1800795 and rs1800796 IL6 polymorphisms and CRC.
|
17694420 |
2007 |
|
Congenital Dysplasia Of The Hip
|
|
0.020 |
GeneticVariation
|
BEFREE |
Data suggest association between TGFB1 29 T → C transition (rs1800470) and IL6 -572G → C transversion (rs1800796) with DDH, and also a possibility of TGF-beta1 and IL-6 interaction in DDH pathogenesis.
|
25603974 |
2015 |
|
Cerebral Palsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
Leukomalacia, Periventricular
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences were found between spastic CP and controls in males for rs2069837; between CP with periventricular leukomalacia and controls in males for rs1800796 and rs2066992; and between term CP and controls in males for rs2069837.
|
24903966 |
2014 |
|
Stomach Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Epidemiological studies have evaluated the associations between interleukin-6 (IL-6) gene -174 C/G (rs1800795) and -572 C/G (rs1800796) polymorphisms and gastric cancer (GC) risk, but results and conclusions remain controversial.
|
22711691 |
2012 |
|
Malignant neoplasm of stomach
|
|
0.040 |
GeneticVariation
|
BEFREE |
Epidemiological studies have evaluated the associations between interleukin-6 (IL-6) gene -174 C/G (rs1800795) and -572 C/G (rs1800796) polymorphisms and gastric cancer (GC) risk, but results and conclusions remain controversial.
|
22711691 |
2012 |
|
Congenital Dysplasia Of The Hip
|
|
0.020 |
GeneticVariation
|
BEFREE |
Further research is needed to validate the weak association between rs1800796 in IL-6 and DDH.
|
28860542 |
2017 |
|
Malignant neoplasm of stomach
|
|
0.040 |
GeneticVariation
|
BEFREE |
Further subgroup analyses based on ethnicities of participants revealed that the IL-4 rs2243250, IL-6 rs1800796 and IL-8 rs4073 polymorphisms were significantly associated with the risk of GC in Asians.
|
30071135 |
2018 |
|
Stomach Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Further subgroup analyses based on ethnicities of participants revealed that the IL-4 rs2243250, IL-6 rs1800796 and IL-8 rs4073 polymorphisms were significantly associated with the risk of GC in Asians.
|
30071135 |
2018 |
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |
|
Colorectal Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.010 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |
|
Malignant neoplasm of stomach
|
|
0.040 |
GeneticVariation
|
BEFREE |
Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer.
|
29552316 |
2018 |