rs1800871, IL19;IL10

N. diseases: 108
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Periodontitis
CUI: C0031099
Disease: Periodontitis
0.010 GeneticVariation BEFREE The studies reviewed support that the IL-10 rs1800871 and rs1800872 polymorphisms may represent a potential genetic biomarker for periodontitis risk in Latin American populations. 30343215 2019
Behcet's uveitis
CUI: C3160901
Disease: Behcet's uveitis
0.010 GeneticVariation BEFREE <i>Results</i>: The risk allele, A, in rs1800871, of <i>IL-10</i> gene was highly prevalent in Behcet's uveitis and healthy control samples alike; highest among the Turkish groups. 29792538 2019
Rhegmatogenous retinal detachment
CUI: C0271055
Disease: Rhegmatogenous retinal detachment
0.010 GeneticVariation BEFREE Differences in genotype distributions between patients with RRD with or without PVR were detected in rs1800795 (IL6) (P = 0.04), rs1800871 (in the vicinity of the IL10) (P = 0.034), and rs1800471 (TGFB1) (P = 0.032). 30807515 2019
Chronic Periodontitis
CUI: C0266929
Disease: Chronic Periodontitis
0.010 GeneticVariation BEFREE The -819C>T(rs1800871) and -592C>A(rs1800872) polymorphisms were both associated with increased CP risk in Latinos under the allele and dominant models. 30295312 2019
Proliferative vitreoretinopathy
CUI: C0242852
Disease: Proliferative vitreoretinopathy
0.010 GeneticVariation BEFREE Differences in genotype distributions between patients with RRD with or without PVR were detected in rs1800795 (IL6) (P = 0.04), rs1800871 (in the vicinity of the IL10) (P = 0.034), and rs1800471 (TGFB1) (P = 0.032). 30807515 2019
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.010 GeneticVariation BEFREE This study aimed to investigate the association between IL-10 gene rs1800896 (-1082 A/G), rs1800871 (-819 T/C), rs1800872 (-592 A/C), and rs3021094 (3388 A/C) single nucleotide polymorphisms (SNPs) and GDM susceptibility. 30873205 2019
Lupus Erythematosus, Systemic
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
0.010 GeneticVariation BEFREE Interleukin 10 gene promoter polymorphisms (rs1800896, rs1800871 and rs1800872) and haplotypes are associated with the activity of systemic lupus erythematosus and IL10 levels in an Iranian population. 30430731 2019
Tuberculosis, Spinal
CUI: C0041330
Disease: Tuberculosis, Spinal
0.010 GeneticVariation BEFREE CONCLUSIONS The rs1800871 (A/G) polymorphism in IL-10 gene is related to the susceptibility to spinal tuberculosis. 31264664 2019
Gastritis, Atrophic
CUI: C0017154
Disease: Gastritis, Atrophic
0.010 GeneticVariation BEFREE The IL10 gene promoter -819C/T (rs1800871) polymorphism was associated with the risk of GC and AG in a Chinese population. 30205739 2018
Autoimmune liver disease
CUI: C0400936
Disease: Autoimmune liver disease
0.010 GeneticVariation BEFREE Our meta-analysis strongly suggests that the IL10 rs1800896, rs1800871, and rs1800872 polymorphisms are not associated with the risk of autoimmune liver disease. 29694797 2018
Cerebral Palsy
CUI: C0007789
Disease: Cerebral Palsy
0.010 GeneticVariation BEFREE The differences in the rs3024490 (<i>p</i> = 0.033) and rs1800871 (<i>p</i> = 0.033) allele frequencies of <i>IL-10</i> were determined between CP patients and controls. 29623066 2018
Recurrent aphthous ulcer
CUI: C2937365
Disease: Recurrent aphthous ulcer
0.010 GeneticVariation BEFREE The minority alleles rs1800871 and rs1800872, which encode variants of IL10, were associated with a statistically significantly higher risk of RAS, as confirmed by the results of genotype and haplotype analyses. 30341786 2018
Bronchiolitis
CUI: C0006271
Disease: Bronchiolitis
0.010 GeneticVariation BEFREE The objective of this study was to evaluate the associations between IL10 single nucleotide polymorphisms (SNPs) at rs1800890 (- 3575A/T), rs1800871 (- 819C/T) or rs1800872 (- 592C/A) either alone or combined with the SNP at rs1800896 (- 1082G/A), and the etiology and severity of infant bronchiolitis. 29802545 2018
Autoimmune hepatitis
CUI: C4721555
Disease: Autoimmune hepatitis
0.010 GeneticVariation BEFREE We performed a meta-analysis to assess the association between three IL10 promoter polymorphisms (rs1800896, rs1800871, and rs1800872) and the risk of autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. 29694797 2018
Ocular Toxoplasmosis
CUI: C0040561
Disease: Ocular Toxoplasmosis
0.010 GeneticVariation BEFREE In contrast, haplotype "AG" of the IL-10 gene promoter polymorphisms (rs1800896 and rs1800871) was present at a lower frequency in OT patients (<i>P</i> = 7e-04; OR = 0.10; 95% CI = 0.03 to 0.35). 29426041 2018
Autoimmune Chronic Hepatitis
CUI: C0241910
Disease: Autoimmune Chronic Hepatitis
0.010 GeneticVariation BEFREE We performed a meta-analysis to assess the association between three IL10 promoter polymorphisms (rs1800896, rs1800871, and rs1800872) and the risk of autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. 29694797 2018
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.010 GeneticVariation BEFREE Promoter variants of TNF-α rs1800629 and IL-10 rs1800871 are independently associated with the susceptibility of coronary artery disease in north Indian. 29734056 2018
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.010 GeneticVariation BEFREE When we stratified data based on ethnicity of participants, we found that the rs1800871 polymorphism was significantly correlated with DM in Caucasians, the rs1800872 polymorphism was significantly correlated with DM in Asians, and the rs1800896 polymorphism was significantly correlated with DM in both Caucasians and Asians. 30223288 2018
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.010 GeneticVariation BEFREE Promoter variants of TNF-α rs1800629 and IL-10 rs1800871 are independently associated with the susceptibility of coronary artery disease in north Indian. 29734056 2018
Psoriasis
CUI: C0033860
Disease: Psoriasis
0.010 GeneticVariation BEFREE Our results suggest that IL-4 (rs2243250) polymorphism is protective against psoriasis, while IL-10 (rs1800871) polymorphism confers increased risk of psoriasis in South Indian Tamils. 28027921 2017
Encephalitis
CUI: C0014038
Disease: Encephalitis
0.010 GeneticVariation BEFREE RESULTS IL-4 rs2227283 and IL-10 rs1800871 have no correlation in with risk of virus-induced encephalitis (both P>0.05) GA and AA genotypes were related to IL-4 rs2227288 and GT, while TT and GT + TT genotypes were related to IL-10 rs1800872. 28935853 2017
Mental disorders
CUI: C0004936
Disease: Mental disorders
0.010 GeneticVariation BEFREE To evaluate MeDi and SA in relation to the presence of rs2020933 (5-HTT), rs1800871 (IL-10) and rs1800629 (TNF-α) polymorphisms. 28314127 2017
IGA Glomerulonephritis
CUI: C0017661
Disease: IGA Glomerulonephritis
0.010 GeneticVariation BEFREE We found that the rs1800896 did not correlate with IgAN risk, whereas rs1800872 and rs1800871 were significantly associated with increased IgAN risk in all genetic models. 28359052 2017
Osteosarcoma
CUI: C0029463
Disease: Osteosarcoma
0.010 GeneticVariation BEFREE However, the genotype and allele frequencies of IL-10 -819C/T (rs1800871) and -592A/C (rs1800872) polymorphisms in osteosarcoma patients did not significantly differ from controls. 26503210 2016
Osteosarcoma of bone
CUI: C0585442
Disease: Osteosarcoma of bone
0.010 GeneticVariation BEFREE However, the genotype and allele frequencies of IL-10 -819C/T (rs1800871) and -592A/C (rs1800872) polymorphisms in osteosarcoma patients did not significantly differ from controls. 26503210 2016