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HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
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0.700 |
SusceptibilityMutation
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CLINVAR |
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Colorectal Carcinoma
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0.040 |
GeneticVariation
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BEFREE |
We found indications that aspirin interacted with rs6983267 close to MYC (encoding a transcription factor involved in cell cycle progression, apoptosis and cellular transformation) and NSAIDs interacted with rs3024505 and rs1800872 in or close to IL10 (encoding IL-10) in preventing CRC.
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24889212 |
2014 |
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Colorectal Carcinoma
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0.040 |
GeneticVariation
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BEFREE |
A decreased risk of colorectal cancer in subjects with rs1800872 AC genotype of IL10 (OR = 0.643, 95%CI = 0.453, 0.912) or AC/CC genotype (OR = 0.636, 95%CI = 0.457, 0.885) was observed, compared with those with AA genotype.
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24762198 |
2014 |
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Colorectal Carcinoma
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0.040 |
GeneticVariation
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BEFREE |
The polymorphisms IL10 C-592A (rs1800872), C-rs3024505-T, IL1b C-3737T (rs4848306), G-1464C (rs1143623), T-31C (rs1143627) and PTGS2 (encoding COX-2) A-1195G (rs689466), G-765C (rs20417), and T8473C (rs5275) were assessed in relation to risk of colorectal cancer (CRC) and interaction with diet (red meat, fish, fibre, cereals, fruit and vegetables) and lifestyle (non-steroid-anti-inflammatory drug use and smoking status) was assessed in a nested case-cohort study of nine hundred and seventy CRC cases and 1789 randomly selected participants from a prospective study of 57,053 persons.
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24194923 |
2013 |
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Colorectal Carcinoma
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0.040 |
GeneticVariation
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BEFREE |
Based on this meta-analysis, we conclude that the IL-10 rs1800872 polymorphism could be a risk factor for CRC development among European populations.
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23079832 |
2012 |
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Malignant neoplasm of breast
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0.030 |
GeneticVariation
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BEFREE |
Moreover, increased BC risks were also associated with the rs1800872 polymorphism (C
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30583340 |
2018 |
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Hepatitis C
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0.030 |
GeneticVariation
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BEFREE |
Only the IL10 promoter rs1800872 SNP was associated with predisposition to chronic hepatitis C. This SNP seems to be a common genetic marker of predisposition to two diseases caused by hepatitis C and tick-borne encephalitis viruses in Russian population.
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29247709 |
2018 |
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Breast Carcinoma
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0.030 |
GeneticVariation
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BEFREE |
Moreover, increased BC risks were also associated with the rs1800872 polymorphism (C
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30583340 |
2018 |
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Tuberculosis, Pulmonary
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0.030 |
GeneticVariation
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BEFREE |
We found correlations between one SNP in IL6 (rs2069837 <i>p</i> = 6.63E-11), seven SNPs in <i>IL10</i> (rs1554286 <i>p</i> = 6.87E-20, rs1518111 <i>p</i> = 6.11E-11, rs3021094 <i>p</i> = 6.75E-29, rs3790622 <i>p</i> = 2.40E-06, rs3024490 <i>p</i> = 6.73E-11, rs1800872 <i>p</i> = 6.18E-11, rs1800871 <i>p</i> = 6.73E-11) and incidences of PTB.
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29662655 |
2018 |
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Inflammatory Bowel Diseases
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0.030 |
GeneticVariation
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BEFREE |
The anti-inflammatory genes, haem oxygenase 1 (HO-1, HMOX1) rs2071746 (unrestricted model: p = 9.07 × 10-4; recessive model: p = 4.99 × 10-4; multiplicative model: p = 0.0009; and additive model: p = 1.87 × 10-4) and interleukin-10 (IL-10) rs1800872 (dominant model: p = 0.0277) have been associated with paediatric inflammatory bowel disease.
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28770550 |
2017 |
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Inflammatory Bowel Diseases
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0.030 |
GeneticVariation
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BEFREE |
The results showed that IL-10 rs304496 was associated with pediatric IBD (<i>P</i> = 0.022), but no association was found for two other IL-10 SNPs, rs1800872 and rs2034498, or for SNPs in genes <i>IL10RA</i>, <i>IL10RB</i>, <i>STAT3</i>, and <i>HO1</i>.
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28785144 |
2017 |
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Malignant neoplasm of esophagus
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0.030 |
GeneticVariation
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BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Malignant neoplasm of mouth
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0.030 |
GeneticVariation
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BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Lip and Oral Cavity Carcinoma
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0.030 |
GeneticVariation
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BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Malignant neoplasm of mouth
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0.030 |
GeneticVariation
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BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Tuberculosis, Pulmonary
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0.030 |
GeneticVariation
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BEFREE |
The aim of this study was to evaluate the association between previously reported SNPs IL2-330 T>G (rs2069762); IL4-590 C>T (rs2243250); IL6-174 G>C (rs1800795); IL10-592 A>C (rs1800872); IL10-1082 G>A (rs1800896); IL17A -692 C>T (rs8193036); IL17A -197 G>A (rs2275913); TNF -238 G>A (rs361525); TNF -308 G>A (rs1800629) and IFNG +874 T>A (rs2430561) and pulmonary TB (PTB) susceptibility.
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26840977 |
2016 |
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Esophageal carcinoma
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0.030 |
GeneticVariation
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BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Lip and Oral Cavity Carcinoma
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|
0.030 |
GeneticVariation
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BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Esophageal carcinoma
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0.030 |
GeneticVariation
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BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Malignant neoplasm of esophagus
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|
0.030 |
GeneticVariation
|
BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Hepatitis C
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0.030 |
GeneticVariation
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BEFREE |
The aim of the present study was to investigate the association between polymorphisms in TNF-α -308 G>A (rs1800629), IL-10 -1082 G>A (rs1800896) and -819/-592 (rs1800871/rs1800872) with HCC risk in individuals with HCV.
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26890368 |
2016 |
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Esophageal Neoplasms
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0.030 |
GeneticVariation
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BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Esophageal Neoplasms
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0.030 |
GeneticVariation
|
BEFREE |
Our results revealed that IL-10 rs1800872 T>G and rs1800896 A>G polymorphisms has a significantly association with the increased risk of esophageal cancer under the allele and dominant models; rs1800871 T>G, rs1800872 T>G and rs1800896 A>G under allele and dominant models could increase the risk of nasopharyngeal cancer; rs1800871T>G, rs1800872T>G and rs1800896 A>G SNPs under allele model were closely related to the susceptibility to oral cancer.
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27002767 |
2016 |
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Esophageal carcinoma
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0.030 |
GeneticVariation
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BEFREE |
However, we did not find significant association of IL-10-819T/C rs1800871 and -592A/C rs1800872 with the development of esophageal cancer.
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26464722 |
2015 |
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Esophageal Neoplasms
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0.030 |
GeneticVariation
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BEFREE |
However, we did not find significant association of IL-10-819T/C rs1800871 and -592A/C rs1800872 with the development of esophageal cancer.
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26464722 |
2015 |