rs1800890, IL19

N. diseases: 29
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
0.010 GeneticVariation BEFREE For diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), joint associations of body mass index (from self-reported height and weight) and 12 polymorphisms in cytokines IL1A (rs1800587), IL1B (rs16944, rs1143627), IL1RN (rs454078), IL2 (rs2069762), IL6 (rs1800795, rs1800797), IL10 (rs1800890, rs1800896), TNF (rs1800629), LTA (rs909253), and CARD15 (rs2066847) were investigated using unconditional logistic regression. 25962811 2015
Diffuse Large B-Cell Lymphoma
CUI: C0079744
Disease: Diffuse Large B-Cell Lymphoma
0.030 GeneticVariation BEFREE In relation to OS, a highly significant interaction was observed in DLBCL for IL4RA (rs1805010) * IL10 (rs1800890) (HR = 0.11 (0.02-0.50)). 26448050 2015
Bronchiolitis
CUI: C0006271
Disease: Bronchiolitis
0.020 GeneticVariation BEFREE IL-10 polymorphisms at rs1800871, rs1800872, rs1800890, and rs1800896 seem to be associated with elevated allergies and/or recurrent wheezing risk in later childhood, after early-life bronchiolitis.Pediatr Pulmonol.2017;52:14-20.© 2016 Wiley Periodicals, Inc. 27228545 2017
Wheezing
CUI: C0043144
Disease: Wheezing
0.010 GeneticVariation BEFREE IL-10 polymorphisms at rs1800871, rs1800872, rs1800890, and rs1800896 seem to be associated with elevated allergies and/or recurrent wheezing risk in later childhood, after early-life bronchiolitis.Pediatr Pulmonol.2017;52:14-20.© 2016 Wiley Periodicals, Inc. 27228545 2017
Lupus Erythematosus, Systemic
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
0.010 GeneticVariation BEFREE There were significant difference in allele and genotype frequency at rs1800890 and rs6667202 between SLE patients with and without thrombocytopenia (rs1800890: P=0.016, P=0.026, respectively; rs6667202: P=0.007, P=0.007, respectively). 29199038 2018
Thrombocytopenia
CUI: C0040034
Disease: Thrombocytopenia
0.010 GeneticVariation BEFREE There were significant difference in allele and genotype frequency at rs1800890 and rs6667202 between SLE patients with and without thrombocytopenia (rs1800890: P=0.016, P=0.026, respectively; rs6667202: P=0.007, P=0.007, respectively). 29199038 2018
Rheumatoid Arthritis
CUI: C0003873
Disease: Rheumatoid Arthritis
0.010 GeneticVariation BEFREE The <i>IL-10</i> rs1800890 variant might contribute to RA susceptibility in the Chinese population. 29487192 2018
Bronchiolitis
CUI: C0006271
Disease: Bronchiolitis
0.020 GeneticVariation BEFREE Infants with rhinovirus bronchiolitis had the IL10 rs1800890 variant AT or TT genotype less often (18.2%) than controls (63.3%, P = 0.03), and likewise, had the IL10 rs1800896 variant AG or GG genotype less often (27.3%) than controls (65.5%, P = 0.009). 29802545 2018
Rhinovirus infection
CUI: C0276447
Disease: Rhinovirus infection
0.010 GeneticVariation BEFREE Infants with rhinovirus bronchiolitis had the IL10 rs1800890 variant AT or TT genotype less often (18.2%) than controls (63.3%, P = 0.03), and likewise, had the IL10 rs1800896 variant AG or GG genotype less often (27.3%) than controls (65.5%, P = 0.009). 29802545 2018