|
Diffuse Large B-Cell Lymphoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
In relation to OS, a highly significant interaction was observed in DLBCL for IL4RA (rs1805010) * IL10 (rs1800890) (HR = 0.11 (0.02-0.50)).
|
26448050 |
2015 |
|
Diffuse Large B-Cell Lymphoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
The study found that polymorphism in interleukin 10 (IL10; rs1800890) modified the association between occupational exposure to organic solvents and the risk for diffuse large B-cell lymphoma (P(for interaction)=0.0058).
|
22609637 |
2013 |
|
Diffuse Large B-Cell Lymphoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
IL10 rs1800890 was associated with risk of diffuse large B-cell lymphoma (OR 1.41, CI 1.08-1.85 for minor allele homozygosity) and mantle cell lymphoma (OR 1.77, CI 1.04-3.00).
|
20087644 |
2010 |
|
Bronchiolitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Infants with rhinovirus bronchiolitis had the IL10 rs1800890 variant AT or TT genotype less often (18.2%) than controls (63.3%, P = 0.03), and likewise, had the IL10 rs1800896 variant AG or GG genotype less often (27.3%) than controls (65.5%, P = 0.009).
|
29802545 |
2018 |
|
Bronchiolitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
IL-10 polymorphisms at rs1800871, rs1800872, rs1800890, and rs1800896 seem to be associated with elevated allergies and/or recurrent wheezing risk in later childhood, after early-life bronchiolitis.Pediatr Pulmonol.2017;52:14-20.© 2016 Wiley Periodicals, Inc.
|
27228545 |
2017 |
|
Adult Diffuse Large B-Cell Lymphoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
The study found that polymorphism in interleukin 10 (IL10; rs1800890) modified the association between occupational exposure to organic solvents and the risk for diffuse large B-cell lymphoma (P(for interaction)=0.0058).
|
22609637 |
2013 |
|
Adult Diffuse Large B-Cell Lymphoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
IL10 rs1800890 was associated with risk of diffuse large B-cell lymphoma (OR 1.41, CI 1.08-1.85 for minor allele homozygosity) and mantle cell lymphoma (OR 1.77, CI 1.04-3.00).
|
20087644 |
2010 |
|
Lymphoma, Non-Hodgkin
|
|
0.020 |
GeneticVariation
|
BEFREE |
We confirmed previous studies showing a polymorphism in the IL10 promoter (rs1800890/-3575T>A) to be associated with non-Hodgkin lymphoma, as this allele was found to be associated with both CLL and WM.
|
19573080 |
2009 |
|
Lymphoma, Non-Hodgkin
|
|
0.020 |
GeneticVariation
|
BEFREE |
Two common single nucleotide polymorphisms in immunoregulatory genes (TNF G308A, rs1800629 and IL10 T3575A, rs1800890) have been recently reported as risk factors for non-Hodgkin lymphoma (NHL) in a large pooled analysis.
|
17510437 |
2007 |
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
There were significant difference in allele and genotype frequency at rs1800890 and rs6667202 between SLE patients with and without thrombocytopenia (rs1800890: P=0.016, P=0.026, respectively; rs6667202: P=0.007, P=0.007, respectively).
|
29199038 |
2018 |
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The <i>IL-10</i> rs1800890 variant might contribute to RA susceptibility in the Chinese population.
|
29487192 |
2018 |
|
Rhinovirus infection
|
|
0.010 |
GeneticVariation
|
BEFREE |
Infants with rhinovirus bronchiolitis had the IL10 rs1800890 variant AT or TT genotype less often (18.2%) than controls (63.3%, P = 0.03), and likewise, had the IL10 rs1800896 variant AG or GG genotype less often (27.3%) than controls (65.5%, P = 0.009).
|
29802545 |
2018 |
|
Thrombocytopenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
There were significant difference in allele and genotype frequency at rs1800890 and rs6667202 between SLE patients with and without thrombocytopenia (rs1800890: P=0.016, P=0.026, respectively; rs6667202: P=0.007, P=0.007, respectively).
|
29199038 |
2018 |
|
Wheezing
|
|
0.010 |
GeneticVariation
|
BEFREE |
IL-10 polymorphisms at rs1800871, rs1800872, rs1800890, and rs1800896 seem to be associated with elevated allergies and/or recurrent wheezing risk in later childhood, after early-life bronchiolitis.Pediatr Pulmonol.2017;52:14-20.© 2016 Wiley Periodicals, Inc.
|
27228545 |
2017 |
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association between interleukin-10-3575T>A (rs1800890) polymorphism and cancer risk.
|
25955784 |
2015 |
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association between interleukin-10-3575T>A (rs1800890) polymorphism and cancer risk.
|
25955784 |
2015 |
|
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
For diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), joint associations of body mass index (from self-reported height and weight) and 12 polymorphisms in cytokines IL1A (rs1800587), IL1B (rs16944, rs1143627), IL1RN (rs454078), IL2 (rs2069762), IL6 (rs1800795, rs1800797), IL10 (rs1800890, rs1800896), TNF (rs1800629), LTA (rs909253), and CARD15 (rs2066847) were investigated using unconditional logistic regression.
|
25962811 |
2015 |
|
Classical Hodgkin's Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated whether selected germline SNPs in IL10 (rs1800890, rs1800896, rs1800871, rs1800872), TNFA (rs1800629), IL6 (rs1800795), ILRN (rs419598), INFG (rs2430561) and CCL17 (rs223828) were associated with circulating levels of related cytokines at diagnosis and progression-free survival (PFS) in CHL.
|
24008079 |
2013 |
|
Adult Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In patients above 40 years, the IL-10 rs1800890 T-allele was associated with lower risk for HL (TT genotype vs. AA, odds ratio [OR] 0.38 [95% confidence interval 0.21-0.69], p = 0.001; AT/TT combined genotypes vs. AA, OR 0.45 [0.27-0.74], p = 0.001).
|
22475179 |
2012 |
|
Hodgkin Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
In patients above 40 years, the IL-10 rs1800890 T-allele was associated with lower risk for HL (TT genotype vs. AA, odds ratio [OR] 0.38 [95% confidence interval 0.21-0.69], p = 0.001; AT/TT combined genotypes vs. AA, OR 0.45 [0.27-0.74], p = 0.001).
|
22475179 |
2012 |
|
Childhood Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In patients above 40 years, the IL-10 rs1800890 T-allele was associated with lower risk for HL (TT genotype vs. AA, odds ratio [OR] 0.38 [95% confidence interval 0.21-0.69], p = 0.001; AT/TT combined genotypes vs. AA, OR 0.45 [0.27-0.74], p = 0.001).
|
22475179 |
2012 |
|
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
|
|
0.010 |
GeneticVariation
|
BEFREE |
IL10 rs1800890 was associated with risk of diffuse large B-cell lymphoma (OR 1.41, CI 1.08-1.85 for minor allele homozygosity) and mantle cell lymphoma (OR 1.77, CI 1.04-3.00).
|
20087644 |
2010 |
|
Mantle cell lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
IL10 rs1800890 was associated with risk of diffuse large B-cell lymphoma (OR 1.41, CI 1.08-1.85 for minor allele homozygosity) and mantle cell lymphoma (OR 1.77, CI 1.04-3.00).
|
20087644 |
2010 |
|
Malignant neoplasm of prostate
|
|
0.010 |
GeneticVariation
|
BEFREE |
Associations of IL10 haplotypes with prostate cancer were explained by high linkage disequilibrium between two tagSNPs (rs1800890 and rs3024496) and -1082G>A.
|
19267370 |
2009 |
|
Waldenstrom Macroglobulinemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
We confirmed previous studies showing a polymorphism in the IL10 promoter (rs1800890/-3575T>A) to be associated with non-Hodgkin lymphoma, as this allele was found to be associated with both CLL and WM.
|
19573080 |
2009 |