rs2000813, LIPG

N. diseases: 9
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Autistic Disorder
CUI: C0004352
Disease: Autistic Disorder
0.700 GeneticVariation GWASDB Individual common variants exert weak effects on the risk for autism spectrum disorders. 22843504 2012
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.030 GeneticVariation BEFREE To investigate the relationship between the common single nucleotide polymorphisms (SNPs) 584C/T (rs2000813) and -384A/C (rs3813082) in the LIPG gene and CAD, allele and genotype frequencies of the two SNPs were analysed in 287 Chinese patients with CAD and 367 controls by the high-resolution melting curve (HRM) method. 26124511 2015
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.030 GeneticVariation BEFREE Our data support a modest association between the LIPG rs2000813 variant and parameters of HDL metabolism, but no association between common genetic variants in LIPG and CAD or DVT risk. 20466371 2010
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.030 GeneticVariation BEFREE The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. 19411665 2009
Diabetes Mellitus, Non-Insulin-Dependent
0.020 GeneticVariation BEFREE In hyperlipidemic patients, apart from its known association with HDL-C, CETP Taq1B is also associated with A1C levels, and both associations are modified by type 2 diabetes and LIPG Thr111Ile. 27590083 2016
Diabetes Mellitus, Non-Insulin-Dependent
0.020 GeneticVariation BEFREE Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients. 24852509 2014
Diabetic Retinopathy
CUI: C0011884
Disease: Diabetic Retinopathy
0.010 GeneticVariation BEFREE Our previous study demonstrated that the endothelial lipase (EL) C.584C>T polymorphism (rs2000813, p.Thr111Ile) was significantly associated with diabetic retinopathy (DR). 24852509 2014
Proliferative retinopathy
CUI: C0339467
Disease: Proliferative retinopathy
0.010 GeneticVariation BEFREE Association of endothelial lipase Thr111Ile polymorphism with proliferative retinopathy in type 2 diabetes patients. 24852509 2014
Deep Vein Thrombosis
CUI: C0149871
Disease: Deep Vein Thrombosis
0.010 GeneticVariation BEFREE Our data support a modest association between the LIPG rs2000813 variant and parameters of HDL metabolism, but no association between common genetic variants in LIPG and CAD or DVT risk. 20466371 2010
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.010 GeneticVariation BEFREE Our analysis among healthy Caucasian men and women from three independent studies does not support an association between the T111I variant and HDL-C, other plasma lipids, or risk of CHD. 19411665 2009
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.010 GeneticVariation BEFREE We examined associations between variants LIPG T111I (rs2000813) and LIPG i24582 (rs6507931), HDL and television viewing/computer use ("screen time") as a marker for physical inactivity in a population with high prevalence of metabolic syndrome. 19380136 2009
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.010 GeneticVariation BEFREE The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. 19411665 2009