|
Psoriasis
|
|
0.860 |
GeneticVariation
|
BEFREE |
In contrast, the lack of any association between rs20541 (IL13) and psoriasis in our Egyptian cohort suggests the existence of important inter-ethnic genetic differences in psoriasis susceptibility.
|
25406098 |
2015 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
GWASCAT |
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
|
25903422 |
2015 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
GWASCAT |
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
|
26626624 |
2015 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
BEFREE |
In subgroup analyses, the two SNPs were significantly associated (P < 0.05) with type I psoriasis, Rs495337 showed statistically difference between positive family history of psoriasis patients and controls whereas rs20541 might preferentially associated with negative family history psoriasis patients.
|
23617596 |
2013 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
BEFREE |
Evidence for an association between EBV-negative cHL and rs20541 (5q31, IL13: OR = 1.53, 95% CI = 1.32 to 1.76, P = 5.4 x 10(-9)), a variant previously linked to psoriasis and asthma, was observed; however, the evidence for replication was less clear.
|
22286212 |
2012 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
BEFREE |
The minor allele T of rs20541 in IL13 is the risk allele for asthma but the protective allele for psoriasis.
|
22694930 |
2012 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
BEFREE |
The authors genotyped three groups of Caucasians: those with PsA, those with psoriasis without arthritis (PsC) and healthy controls for the rs20541 and rs848 IL13 single nucleotide polymorphisms (SNPs).
|
21613309 |
2011 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
GWASDB |
Association analyses identify six new psoriasis susceptibility loci in the Chinese population.
|
20953187 |
2010 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
GWASDB |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
GWASCAT |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
BEFREE |
A multitiered genetic association study of 25 215 single-nucleotide polymorphisms (SNPs) in three case-control sample sets (1446 patients and 1432 controls) identified three IL13-linked SNPs (rs1800925, rs20541 and rs848) associated with psoriasis.
|
18075513 |
2008 |
|
Hodgkin Disease
|
|
0.810 |
GeneticVariation
|
GWASDB |
A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.
|
24920014 |
2014 |
|
Hodgkin Disease
|
|
0.810 |
GeneticVariation
|
BEFREE |
We searched for an association between the interleukin 4 receptor gene (IL4R) rs1805015 and interleukin 13 gene (IL13) rs20541 polymorphisms and the development of antibodies to hepatitis B surface antigen (anti-HBs) in the case of hepatitis B virus (HBV) vaccination or infection in hemodialysis (HD) patients.
|
23462527 |
2013 |
|
Hodgkin Disease
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups.
|
22286212 |
2012 |
|
Hodgkin Disease
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of classical Hodgkin lymphoma and Epstein-Barr virus status-defined subgroups.
|
22286212 |
2012 |
|
Asthma
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
|
29273806 |
2018 |
|
Asthma
|
|
0.800 |
GeneticVariation
|
BEFREE |
These results support the existence of a significant association between GSTP1 rs1695 and IL13 rs20541 SNPs, with susceptibility to asthma, in the population studied.
|
27561723 |
2018 |
|
Asthma
|
|
0.800 |
GeneticVariation
|
BEFREE |
IL-13 minor T and A alleles for rs1295686 and rs20541, respectively, were associated with significantly higher risk of asthma in the Saudi Arabian population.
|
29211635 |
2018 |
|
Asthma
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
|
29273806 |
2018 |
|
Asthma
|
|
0.800 |
GeneticVariation
|
BEFREE |
Self-Reported Allergic Rhinitis and/or Allergic Conjunctivitis Associate with IL13 rs20541 Polymorphism in Finnish Adult Asthma Patients.
|
28273659 |
2017 |
|
Allergic Reaction
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
|
23817569 |
2013 |
|
Allergic Reaction
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
|
23817569 |
2013 |
|
Asthma
|
|
0.800 |
GeneticVariation
|
BEFREE |
ICSNPathway analysis identified four candidate causal SNPs, four genes, and 21 candidate causal pathways, which in total provided four hypothetical biologic mechanisms: (1) rs7192 (nonsynonymous coding) to HLA-DRA to 21 pathways, such as, the role of eosinophils in the chemokine network of allergy, Th1/Th2 differentiation, and asthma (nominal p ≤ 0.001, FDR p ≤ 0.01); (2) rs20541 (nonsynonymous coding) to IL13 to asthma and cytokines and inflammatory response (nominal p<0.001, FDR p ≤ 0.008); (3) rs1058808 (frameshift coding) to ERBB2 to transmembrane receptor activity (nominal p=0.001, FDR p=0.01); (4) rs17350764 (nonsynonymous coding (deleterious)) to OR52J3 to transmembrane receptor activity (nominal p=0.001, FDR p=0.01).
|
23200760 |
2013 |
|
Asthma
|
|
0.800 |
GeneticVariation
|
BEFREE |
Evidence for an association between EBV-negative cHL and rs20541 (5q31, IL13: OR = 1.53, 95% CI = 1.32 to 1.76, P = 5.4 x 10(-9)), a variant previously linked to psoriasis and asthma, was observed; however, the evidence for replication was less clear.
|
22286212 |
2012 |
|
Asthma
|
|
0.800 |
GeneticVariation
|
BEFREE |
To investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.
|
22376040 |
2012 |