rs2071286, NOTCH4

N. diseases: 12
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cryoglobulinemia
CUI: C0010403
Disease: Cryoglobulinemia
0.700 GeneticVariation GWASCAT Genome-wide association study of hepatitis C virus- and cryoglobulin-related vasculitis. 25030430 2014
Hepatitis C, Chronic
CUI: C0524910
Disease: Hepatitis C, Chronic
0.700 GeneticVariation GWASCAT Genome-wide association study of hepatitis C virus- and cryoglobulin-related vasculitis. 25030430 2014
Pemphigus Vulgaris
CUI: C0030809
Disease: Pemphigus Vulgaris
0.700 GeneticVariation GWASDB Population-specific association between a polymorphic variant in ST18, encoding a pro-apoptotic molecule, and pemphigus vulgaris. 22437316 2012
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.700 GeneticVariation GWASDB Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. 20383147 2010
Benign Lymphoproliferative Disorder
CUI: C0746351
Disease: Benign Lymphoproliferative Disorder
0.010 GeneticVariation BEFREE This data shows that the previously demonstrated association between NOTCH4 rs2071286 and HLA-II rs9461776 polymorphisms and HCV-related MCS could be extended to overall patients with HCV-related LPDs. 29069725 2017
Childhood Lymphoma
CUI: C1332979
Disease: Childhood Lymphoma
0.010 GeneticVariation BEFREE The significant relationship between rs2071286 and rs9461776 MAF and the increased risk for NHL, suggests their use as non-invasive markers to categorize patients at risk of lymphoma. 29069725 2017
Mixed cryoglobulinemia
CUI: C0543697
Disease: Mixed cryoglobulinemia
0.010 GeneticVariation BEFREE We analyzed NOTCH4 rs2071286 and HLA-II rs9461776 in 3 HCV-related LPD groups (asymptomatic MC, MCS, NHL) with HCV infection without lymphoproliferative disorders. 29069725 2017
Lymphoproliferative Disorders
CUI: C0024314
Disease: Lymphoproliferative Disorders
0.010 GeneticVariation BEFREE We analyzed NOTCH4 rs2071286 and HLA-II rs9461776 in 3 HCV-related LPD groups (asymptomatic MC, MCS, NHL) with HCV infection without lymphoproliferative disorders. 29069725 2017
Lymphoma
CUI: C0024299
Disease: Lymphoma
0.010 GeneticVariation BEFREE The significant relationship between rs2071286 and rs9461776 MAF and the increased risk for NHL, suggests their use as non-invasive markers to categorize patients at risk of lymphoma. 29069725 2017
Adult Lymphoma
CUI: C1332206
Disease: Adult Lymphoma
0.010 GeneticVariation BEFREE The significant relationship between rs2071286 and rs9461776 MAF and the increased risk for NHL, suggests their use as non-invasive markers to categorize patients at risk of lymphoma. 29069725 2017
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.010 GeneticVariation BEFREE We analyzed NOTCH4 rs2071286 and HLA-II rs9461776 in 3 HCV-related LPD groups (asymptomatic MC, MCS, NHL) with HCV infection without lymphoproliferative disorders. 29069725 2017
Lymphoma, Non-Hodgkin
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
0.010 GeneticVariation BEFREE The significant relationship between rs2071286 and rs9461776 MAF and the increased risk for NHL, suggests their use as non-invasive markers to categorize patients at risk of lymphoma. 29069725 2017