|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.810 |
GeneticVariation
|
BEFREE |
However, even in never-drinkers, minor allele homozygote strongly influenced T2D risk reduction (rs2074356 for AA: HR = 0.35, 95% CI = 0.14-0.90, and p-trend = 0.0035 in men and HR = 0.34, 95% CI = 0.13-0.93, and p-trend = 0.2348 in women; rs11066280 for AA: HR = 0.36, 95% CI = 0.16-0.82, and p-trend = 0.0014 in men and HR = 0.39, 95% CI = 0.16-0.95, and p-trend = 0.3790 in women), while alcohol consumption did not influence the risk of T2D within each genotype. rs2074356 and rs11066280 in or near C12orf51, which is related to alcohol drinking behavior, may longitudinally decrease the risk of T2D, but not through regulation of alcohol consumption.
|
26891264 |
2016 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.810 |
GeneticVariation
|
GWASCAT |
New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.
|
23575436 |
2013 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.810 |
GeneticVariation
|
GWASDB |
New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.
|
23575436 |
2013 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.
|
30718733 |
2019 |
|
Alcohol consumption
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
|
28485404 |
2017 |
|
Alcohol consumption
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.
|
23555315 |
2013 |
|
Blood urea nitrogen measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
|
22797727 |
2012 |
|
Blood urea nitrogen measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
|
22797727 |
2012 |
|
Alcohol consumption
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men.
|
21270382 |
2011 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
|
21909109 |
2011 |
|
Esophageal Neoplasms
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.
|
21642993 |
2011 |
|
Alcohol consumption
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men.
|
21270382 |
2011 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
|
21909109 |
2011 |
|
Esophageal Neoplasms
|
|
0.800 |
GeneticVariation
|
GWASDB |
Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.
|
20833657 |
2010 |
|
Waist-Hip Ratio
|
|
0.800 |
GeneticVariation
|
GWASDB |
For waist-hip ratio, variants on chromosome 12q24 (rs2074356, P = 7.8 x 10(-12)) showed convincing associations, although no regional transcript has strong biological candidacy.
|
19396169 |
2009 |
|
Waist-Hip Ratio
|
|
0.800 |
GeneticVariation
|
GWASCAT |
For waist-hip ratio, variants on chromosome 12q24 (rs2074356, P = 7.8 x 10(-12)) showed convincing associations, although no regional transcript has strong biological candidacy.
|
19396169 |
2009 |
|
Metabolic Syndrome X
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.
|
30382898 |
2018 |
|
Mean Corpuscular Volume (result)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.
|
28017375 |
2017 |
|
Coronary heart disease
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of a coronary artery disease risk variant.
|
23364394 |
2013 |
|
Major Depressive Disorder
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.
|
23377640 |
2013 |
|
Drinking behavior processes
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common variants at 12q24 are associated with drinking behavior in Han Chinese.
|
23364009 |
2013 |
|
Coronary heart disease
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary artery disease in the Japanese.
|
21971053 |
2012 |
|
Serum gamma-glutamyl transferase measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
|
21909109 |
2011 |
|
Malignant neoplasm of esophagus
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.
|
21642993 |
2011 |
|
Gamma glutamyl transferase measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
|
21909109 |
2011 |