rs213210, MIR219A1;RING1

N. diseases: 11
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.700 GeneticVariation GWASDB A genome-wide association study identifies two new cervical cancer susceptibility loci at 4q12 and 17q12. 23817570 2013
Non-Small Cell Lung Carcinoma
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
0.020 GeneticVariation BEFREE We found that CC genotype in rs213210 (OR=3.462, 95%CI=2.222-5.394, <i>P</i><0.001) compared with TT genotype and GG genotype in rs107822 (OR=3.553, 95%CI=2.329-5.419, <i>P</i><0.001) compared with AA genotype showed significantly increased risk of NSCLC. 28915609 2017
Non-Small Cell Lung Carcinoma
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
0.020 GeneticVariation BEFREE Five SNPs found in pre-miRNAs (rs11614913/miR-196a2, rs2910164/miR-146a, rs6505162/miR-423, rs2289030/miR-492, and rs895819/miR-27a) and 2 SNPs found in pri-miRNAs (rs7372209/miR-26a-1 and rs213210/miR-219-1) were genotyped in 388 patients with NSCLC. 22818121 2012
Acute lymphocytic leukemia
CUI: C0023449
Disease: Acute lymphocytic leukemia
0.010 GeneticVariation BEFREE For patients with ALL, the increased risk of post-HSCT relapse was associated with the donor SNP of rs213210 in the RING1 gene promoter, and the recipient SNPs of rs79327197 in the HLA-DOA gene promoter, rs2009658 in the telomeric end of lymphotoxin-alpha (LTA) gene, rs17220087 and rs17213693 in the intron of HLA-DOB gene, and rs2070120 in the 3'-UTR of HLA-DOB gene. 31551439 2019
Leukemia, Myelocytic, Acute
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
0.010 GeneticVariation BEFREE For patients with AML, the increased risk of post-HSCT relapse was associated with the donor SNP of rs111394117 in the intron of NOTCH4 gene, and the recipient SNPs of rs213210 in the ring finger protein 1 (RING1) gene promoter, and rs17220087 and rs17213693 in the intron of HLA-DOB gene. 31551439 2019
Malignant neoplasm of lung
CUI: C0242379
Disease: Malignant neoplasm of lung
0.010 GeneticVariation BEFREE Overall, these findings firstly showed that rs213210 and rs107822 could be meaningful as genetic markers for lung cancer risk. 28915609 2017
Primary malignant neoplasm of lung
CUI: C1306460
Disease: Primary malignant neoplasm of lung
0.010 GeneticVariation BEFREE Overall, these findings firstly showed that rs213210 and rs107822 could be meaningful as genetic markers for lung cancer risk. 28915609 2017
Carcinoma of lung
CUI: C0684249
Disease: Carcinoma of lung
0.010 GeneticVariation BEFREE Overall, these findings firstly showed that rs213210 and rs107822 could be meaningful as genetic markers for lung cancer risk. 28915609 2017
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.010 GeneticVariation BEFREE The C/T or C/C genotypes of rs213210</span> were related to a lower GC risk (OR = 0.76, 95% CI: 0.62-0.93, <i>P</i> = 0.009) compared to the T/T genotype. 28298809 2017
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.010 GeneticVariation BEFREE The C/T or C/C genotypes of rs213210</span> were related to a lower GC risk (OR = 0.76, 95% CI: 0.62-0.93, <i>P</i> = 0.009) compared to the T/T genotype. 28298809 2017
Squamous cell carcinoma of esophagus
0.010 GeneticVariation BEFREE Furthermore, two miR-219-1 SNPs, namely, rs107822 and rs213210, may tag each other to decrease the risk of Kazakh ESCC. 26379361 2015
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.010 GeneticVariation BEFREE Two SNPs (rs4919510 in miR-608 and rs213210 in miR-219-1) were genotyped in 1083 CRC patients recruited in the Czech Republic to evaluate their effect on clinical outcomes. 25368035 2015