|
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
The association analyses revealed no difference in Arg201Gly genotype frequency between patients and controls, neither overall nor for different subgroups according to site of tumour, gender, age at diagnosis, family history of colorectal cancer and modified Dukes classification.
|
15646429 |
2004 |
|
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Codon 201Arg/Gly polymorphism in tumor tissues did not differ from that in the corresponding normal tissues, except for 10 cases of carcinoma with loss of heterozygosity (LOH).
|
9440618 |
1997 |
|
Malignant neoplasm of breast
|
|
0.010 |
GeneticVariation
|
BEFREE |
An age-stratified analysis revealed an association between rs2229080 and reduced breast cancer risk among older patients (≥ 49 years).
|
27127179 |
2016 |
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
An age-stratified analysis revealed an association between rs2229080 and reduced breast cancer risk among older patients (≥ 49 years).
|
27127179 |
2016 |
|
Schizophrenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results first suggested that the allelic and genotypic frequencies of the DCC polymorphism rs2229080 were nominally associated with schizophrenia.
|
27055860 |
2016 |
|
Neoplasm Metastasis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, rs2229080 was associated with the axillary lymph node (LN) metastasis status.
|
27127179 |
2016 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.010 |
GeneticVariation
|
BEFREE |
No association was observed between the Arg201Gly polymorphism of DCC and colorectal cancer risk.
|
15646429 |
2004 |
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
No association was observed between the Arg201Gly polymorphism of DCC and colorectal cancer risk.
|
15646429 |
2004 |
|
Autoimmune Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
There was no evidence for association of DCC nt 601 C --> G with autoimmune disease in cohorts comprising 2253 subjects with rheumatoid arthritis, type I diabetes and Graves' disease, and 2225 control subjects, from New Zealand and the United Kingdom.
|
14571268 |
2003 |
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
There was no evidence for association of DCC nt 601 C --> G with autoimmune disease in cohorts comprising 2253 subjects with rheumatoid arthritis, type I diabetes and Graves' disease, and 2225 control subjects, from New Zealand and the United Kingdom.
|
14571268 |
2003 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
Furthermore, using the transmission disequilibrium test, there was no significant evidence for biased transmission of the nt 601 C --> G polymorphism to probands within a 382 family type I diabetes affected sibpair cohort from the United Kingdom.
|
14571268 |
2003 |
|
Ewings sarcoma-primitive neuroectodermal tumor (PNET)
|
|
0.010 |
GeneticVariation
|
BEFREE |
Reduced or absent expression and codon 201Gly/Arg polymorphism of DCC gene in rhabdomyosarcoma and Ewing's sarcoma/PNET family.
|
10998440 |
2000 |
|
Rhabdomyosarcoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Reduced or absent expression and codon 201Gly/Arg polymorphism of DCC gene in rhabdomyosarcoma and Ewing's sarcoma/PNET family.
|
10998440 |
2000 |
|
Adult Rhabdomyosarcoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Reduced or absent expression and codon 201Gly/Arg polymorphism of DCC gene in rhabdomyosarcoma and Ewing's sarcoma/PNET family.
|
10998440 |
2000 |
|
Childhood Rhabdomyosarcoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Reduced or absent expression and codon 201Gly/Arg polymorphism of DCC gene in rhabdomyosarcoma and Ewing's sarcoma/PNET family.
|
10998440 |
2000 |
|
Colorectal Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Codon 201Arg/Gly polymorphism of DCC (deleted in colorectal carcinoma) gene in flat- and polypoid-type colorectal tumors.
|
9440618 |
1997 |
|
Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
To elucidate further genetic alterations in flat-type colorectal tumors, codon 201Arg/Gly polymorphism in the DCC (deleted in colorectal carcinoma) gene was analyzed in normal tissue (normal colonic mucosa or peripheral lymphocytes) and in tumor tissue from 191 patients with colorectal tumors (36 patients with flat-type colorectal tumors, 81 patients with polypoid-type colorectal tumors, and 74 patients with advanced carcinomas).
|
9440618 |
1997 |