Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASCAT
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
31578528
2019
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASCAT
Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol.
30924126
2019
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
BEFREE
ABCG2 rs2231142 may predict the risk of kidney comorbidities for Chinese Han male gout patients, but not allopurinol response.
31367212
2019
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASCAT
ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study.
29453348
2018
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
BEFREE
The p.Q141K (rs2231142 ) variant had a significantly higher minor allele frequency (0.23) in the gout patients compared with the European-origin population (0.09) and was significantly more common among gout patients than among normouricaemic controls (odds ratio = 3.26, P < 0.0001).
28968913
2017
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASCAT
Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese.
25967671
2015
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASCAT
Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response.
25676789
2015
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASDB
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
23263486
2013
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASDB
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
21768215
2011
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASCAT
Identification of low-frequency variants associated with gout and serum uric acid levels.
21983786
2011
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASDB
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
20884846
2010
Gout
×
CUI:
C0018099
Disease:
Gout
0.820
GeneticVariation
GWASDB
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.
18834626
2008
Arthritis, Gouty
0.810
GeneticVariation
BEFREE
One common ATP-binding cassette subfamily G member 2 (ABCG2) gene variant, which is encoded by the single nucleotide polymorphism (SNP) rs2231142 , was identified to take an essential part in gouty arthritis .
31367212
2019
Arthritis, Gouty
0.810
GeneticVariation
GWASCAT
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
31578528
2019
Arthritis, Gouty
0.810
GeneticVariation
GWASCAT
Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol.
30924126
2019
Arthritis, Gouty
0.810
GeneticVariation
GWASCAT
ABCG2 contributes to the development of gout and hyperuricemia in a genome-wide association study.
29453348
2018
Arthritis, Gouty
0.810
GeneticVariation
GWASCAT
Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response.
25676789
2015
Arthritis, Gouty
0.810
GeneticVariation
GWASCAT
Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese.
25967671
2015
Arthritis, Gouty
0.810
GeneticVariation
GWASDB
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
23263486
2013
Arthritis, Gouty
0.810
GeneticVariation
GWASCAT
Identification of low-frequency variants associated with gout and serum uric acid levels.
21983786
2011
Arthritis, Gouty
0.810
GeneticVariation
GWASDB
Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
21768215
2011
Arthritis, Gouty
0.810
GeneticVariation
GWASDB
Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
20884846
2010
Arthritis, Gouty
0.810
GeneticVariation
GWASDB
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.
18834626
2008
Uric acid measurement (procedure)
0.800
GeneticVariation
GWASCAT
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
31578528
2019
Hyperuricemia
0.800
GeneticVariation
BEFREE
Previous studies have suggested an association between hyperuricemia and gout susceptibility relative to dysfunctional ABCG2 variants, with rs2231142 (Q141K ) being the most common.
30894219
2019