|
Carcinoma of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
However, stratified analysis by cancer type showed evidence that rs2240308 C/T polymorphism had a lower risk in lung cancer (OR, 0.76; 95% CI, 0.63-0.92; P<sub>heterogeneity</sub> = 0.865) and prostate cancer (OR, 0.54; 95% CI, 0.35-0.84; P<sub>heterogeneity</sub> = 0.088) by heterozygote comparison.
|
31038806 |
2019 |
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
However, stratified analysis by cancer type showed evidence that rs2240308 C/T polymorphism had a lower risk in lung cancer (OR, 0.76; 95% CI, 0.63-0.92; P<sub>heterogeneity</sub> = 0.865) and prostate cancer (OR, 0.54; 95% CI, 0.35-0.84; P<sub>heterogeneity</sub> = 0.088) by heterozygote comparison.
|
31038806 |
2019 |
|
Malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
However, stratified analysis by cancer type showed evidence that rs2240308 C/T polymorphism had a lower risk in lung cancer (OR, 0.76; 95% CI, 0.63-0.92; P<sub>heterogeneity</sub> = 0.865) and prostate cancer (OR, 0.54; 95% CI, 0.35-0.84; P<sub>heterogeneity</sub> = 0.088) by heterozygote comparison.
|
31038806 |
2019 |
|
Malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
Moreover, the rs2240308 variant exhibited a significant association with a decreased risk of lung cancer and prostate cancer.
|
28043155 |
2019 |
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
Moreover, the rs2240308 variant exhibited a significant association with a decreased risk of lung cancer and prostate cancer.
|
28043155 |
2019 |
|
Carcinoma of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
Moreover, the rs2240308 variant exhibited a significant association with a decreased risk of lung cancer and prostate cancer.
|
28043155 |
2019 |
|
Carcinoma of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
Three out of seven studied polymorphic sites showed a strong protective effect in subjects having mutant genotype for Axin2 148 C >T and heterozygous genotype for 1365 G > A and 1712 + 19 G > T towards lung cancer risk.
|
28378643 |
2017 |
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
Three out of seven studied polymorphic sites showed a strong protective effect in subjects having mutant genotype for Axin2 148 C >T and heterozygous genotype for 1365 G > A and 1712 + 19 G > T towards lung cancer risk.
|
28378643 |
2017 |
|
Malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
Three out of seven studied polymorphic sites showed a strong protective effect in subjects having mutant genotype for Axin2 148 C >T and heterozygous genotype for 1365 G > A and 1712 + 19 G > T towards lung cancer risk.
|
28378643 |
2017 |
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
AXIN2 polymorphism rs2240308 was also associated with decreased cancer risk under all five models in lung cancer.
|
25974148 |
2015 |
|
Carcinoma of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
AXIN2 polymorphism rs2240308 was also associated with decreased cancer risk under all five models in lung cancer.
|
25974148 |
2015 |
|
Malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
AXIN2 polymorphism rs2240308 was also associated with decreased cancer risk under all five models in lung cancer.
|
25974148 |
2015 |
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
Findings from this study suggest that Axin2 exon1 T148C polymorphism (rs2240308) contributes to increased susceptibility to lung cancer in Chinese population.
|
25091576 |
2014 |
|
Carcinoma of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
Findings from this study suggest that Axin2 exon1 T148C polymorphism (rs2240308) contributes to increased susceptibility to lung cancer in Chinese population.
|
25091576 |
2014 |
|
Malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
No significant association was found between rs2240308</span> polymorphism and histological subtypes of lung cancers.
|
25091576 |
2014 |
|
Malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
These results suggest that the AXIN2 Pro50Ser SNP is associated with development of lung cancer as a protective SNP, while an association between the AXIN2 SNP and risk of colorectal cancer and of head and neck cancer was not observed.
|
16820935 |
2006 |
|
Carcinoma of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
These results suggest that the AXIN2 Pro50Ser SNP is associated with development of lung cancer as a protective SNP, while an association between the AXIN2 SNP and risk of colorectal cancer and of head and neck cancer was not observed.
|
16820935 |
2006 |
|
Primary malignant neoplasm of lung
|
|
0.060 |
GeneticVariation
|
BEFREE |
These results suggest that the AXIN2 Pro50Ser SNP is associated with development of lung cancer as a protective SNP, while an association between the AXIN2 SNP and risk of colorectal cancer and of head and neck cancer was not observed.
|
16820935 |
2006 |
|
Malignant neoplasm of prostate
|
|
0.030 |
GeneticVariation
|
BEFREE |
In conclusion, this pooled analysis suggested that AXIN2 rs2240308 C/T variant may decrease both lung and prostate cancer susceptibility, particularly in Asian descendants and population-based studies.
|
31038806 |
2019 |
|
Malignant Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
However, stratified analysis by cancer type showed evidence that rs2240308 C/T polymorphism had a lower risk in lung cancer (OR, 0.76; 95% CI, 0.63-0.92; P<sub>heterogeneity</sub> = 0.865) and prostate cancer (OR, 0.54; 95% CI, 0.35-0.84; P<sub>heterogeneity</sub> = 0.088) by heterozygote comparison.
|
31038806 |
2019 |
|
Malignant Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
These findings indicate that further replication studies with large sample sizes are warranted </span>to re-evaluate the relationship between Axin2 rs2240308 and cancer risk, especially in Caucasians.
|
28043155 |
2019 |
|
Malignant neoplasm of prostate
|
|
0.030 |
GeneticVariation
|
BEFREE |
Moreover, the rs2240308 variant exhibited a significant association with a decreased risk of lung cancer and prostate cancer.
|
28043155 |
2019 |
|
Prostate carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Moreover, the rs2240308 variant exhibited a significant association with a decreased risk of lung cancer and prostate cancer.
|
28043155 |
2019 |
|
Prostate carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
In conclusion, this pooled analysis suggested that AXIN2 rs2240308 C/T variant may decrease both lung and prostate cancer susceptibility, particularly in Asian descendants and population-based studies.
|
31038806 |
2019 |
|
Primary malignant neoplasm
|
|
0.030 |
GeneticVariation
|
BEFREE |
These findings indicate that further replication studies with large sample sizes are warranted </span>to re-evaluate the relationship between Axin2 rs2240308 and cancer risk, especially in Caucasians.
|
28043155 |
2019 |