rs2269067, C5

N. diseases: 5
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE C5 rs2269067 GG genotype confers risk for PDR of T2D in Chinese han population and is associated with an elevated C5 mRNA expression and an increased IL-6 production. 26934706 2016
PIGMENTARY DISORDER, RETICULATE, WITH SYSTEMIC MANIFESTATIONS
CUI: C1845050
Disease: PIGMENTARY DISORDER, RETICULATE, WITH SYSTEMIC MANIFESTATIONS
0.010 GeneticVariation BEFREE C5 rs2269067 GG genotype confers risk for PDR of T2D in Chinese han population and is associated with an elevated C5 mRNA expression and an increased IL-6 production. 26934706 2016
Ankylosing spondylitis
CUI: C0038013
Disease: Ankylosing spondylitis
0.010 GeneticVariation BEFREE The frequency of the GG genotype of rs2269067 in C5 was increased in AAU patients with or without AS compared to controls (Pc = 4.0 × 10(-5), odds ratio [OR] = 1.94 and Pc = 9.4 × 10(-5), OR = 1.89, respectively). 26230759 2015
Behcet Syndrome
CUI: C0004943
Disease: Behcet Syndrome
0.010 GeneticVariation BEFREE Increased frequencies of the GG genotype of C3 rs408290 and C5 rs2269067 were found in BD. 26269006 2015
Acute anterior uveitis
CUI: C0701807
Disease: Acute anterior uveitis
0.010 GeneticVariation BEFREE The C5 rs2269067 GG genotype confers risk for AAU in a Chinese population and is associated with an elevated C5 serum concentration and an increased IL-17 production. 26230759 2015