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MILES-CARPENTER X-LINKED MENTAL RETARDATION SYNDROME
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0.010 |
GeneticVariation
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BEFREE |
Given the reported association of nitric oxide synthase (NOS) gene polymorphisms with inflammatory disorders, we aimed to investigate the distribution of NOS2A -2.5 kb (CCTTT) n as well as Ser608Leu and NOS3 -786T>C variants and their correlation with nitrite/nitrate levels, in a study cohort including 170 MCS, 108 suspected MCS (SMCS), 89 FM/CFS, and 196 healthy subjects.
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25878398 |
2015 |
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Peptic Esophagitis
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0.010 |
GeneticVariation
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BEFREE |
There was no significant association between this polymorphism and risk of Barrett's esophagus or reflux esophagitis or between the iNOS Ser 608 Leu polymorphism and risk of these esophageal conditions.
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18349295 |
2008 |
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Pregnancy associated hypertension
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0.010 |
GeneticVariation
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BEFREE |
We examined whether two functional, clinically relevant iNOS genetic polymorphisms (the C(-1026)A polymorphism, rs2779249, in the promoter region, and the G2087A polymorphism, rs2297518, in exon 16) are associated with GH or with PE.
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21716319 |
2012 |
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Primary malignant neoplasm
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0.020 |
GeneticVariation
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BEFREE |
The aim of this study was to evaluate the association of NOS2 polymorphisms Ser608Leu (rs2297518) in exon 16, -954G/C and -1173C/T, both in the promoter region, with gastric cancer and chronic gastritis and the association of cancer with risk factors such as smoking, alcohol intake and H. pylori infection.
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20565800 |
2010 |
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Primary malignant neoplasm
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0.020 |
GeneticVariation
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BEFREE |
The results indicated that the polymorphisms in iNOS gene (C150T(Ser(608) Leu) polymorphism and polymorphic (CCTTT)n repeats) had no association with cancer risk for all genetic models.
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26391304 |
2015 |
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Prostate carcinoma
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0.010 |
GeneticVariation
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BEFREE |
We evaluated the association of prostate cancer with genetic polymorphisms in two genes related to intracellular NO: NOS2A [inducible nitric oxide synthase (NOS); -2892T>C, Ex16 + 14C>T (S608L), IVS16 + 88T>G and IVS20 + 524G>A] and NOS3 [endothelial NOS; IVS1-762C>T, Ex7-43C>T (D258D), IVS7-26A>G, Ex8-63G>T (E298D) and IVS15-62G>T].
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19168583 |
2009 |
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Recurrent aphthous ulcer
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0.010 |
GeneticVariation
|
BEFREE |
Inheritence of a NOS2 single-nucleotide polymorphism rs2297518 is associated with increased risk of recurrent aphthous stomatitis in a Jordanian population.
|
21481004 |
2011 |
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Sepsis
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0.010 |
GeneticVariation
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BEFREE |
Our findings suggest that the NOS2 rs2297518 may play a role in mediating the susceptibility to septic shock in patients with sepsis in Chinese populations.
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23192595 |
2013 |
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Septicemia
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0.010 |
GeneticVariation
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BEFREE |
Our findings suggest that the NOS2 rs2297518 may play a role in mediating the susceptibility to septic shock in patients with sepsis in Chinese populations.
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23192595 |
2013 |
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Stomach Carcinoma
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0.020 |
GeneticVariation
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BEFREE |
<i>iNOS</i> rs2297518 and <i>eNOS</i> rs2070744 polymorphisms may represent susceptible factors for gastric cancer.
|
29765229 |
2018 |
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Stomach Carcinoma
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|
0.020 |
GeneticVariation
|
BEFREE |
SNP Ser608Leu was not associated with risk of chronic gastritis or gastric cancer.
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20565800 |
2010 |