rs2301436, FGFR1OP

N. diseases: 11
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Crohn Disease
CUI: C0010346
Disease: Crohn Disease
0.810 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Crohn Disease
CUI: C0010346
Disease: Crohn Disease
0.810 GeneticVariation BEFREE Here, we studied the susceptibility nature of three components of IL23 signalling and Th17 cell differentiation: JAK2 rs10758669, STAT3 rs744166 and CCR6 rs2301436 initially associated with CD in Hungarian CD and UC patients. 22269120 2012
Crohn Disease
CUI: C0010346
Disease: Crohn Disease
0.810 GeneticVariation GWASCAT Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. 20570966 2010
Crohn Disease
CUI: C0010346
Disease: Crohn Disease
0.810 GeneticVariation GWASDB Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. 20570966 2010
Crohn Disease
CUI: C0010346
Disease: Crohn Disease
0.810 GeneticVariation GWASDB Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394 2008
Crohn Disease
CUI: C0010346
Disease: Crohn Disease
0.810 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394 2008
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.710 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.710 GeneticVariation BEFREE Here, we studied the susceptibility nature of three components of IL23 signalling and Th17 cell differentiation: JAK2 rs10758669, STAT3 rs744166 and CCR6 rs2301436 initially associated with CD in Hungarian CD and UC patients. 22269120 2012
Psoriasis
CUI: C0033860
Disease: Psoriasis
0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Ankylosing spondylitis
CUI: C0038013
Disease: Ankylosing spondylitis
0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Cholangitis, Sclerosing
CUI: C0008313
Disease: Cholangitis, Sclerosing
0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
Multiple Sclerosis
CUI: C0026769
Disease: Multiple Sclerosis
0.700 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364 2011
Asthma
CUI: C0004096
Disease: Asthma
0.700 GeneticVariation GWASDB Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. 21150878 2011
Graves Disease
CUI: C0018213
Disease: Graves Disease
0.700 GeneticVariation GWASDB A genome-wide association study identifies two new risk loci for Graves' disease. 21841780 2011
Uveomeningoencephalitic Syndrome
CUI: C0042170
Disease: Uveomeningoencephalitic Syndrome
0.010 GeneticVariation BEFREE These results suggest that the rs2301436 tagSNP of FGFR10P is positively associated with susceptibility to VKH syndrome in the tested Chinese Han populations. 23935994 2013
Invasive Fungal Infections
CUI: C1262313
Disease: Invasive Fungal Infections
0.010 GeneticVariation BEFREE In parallel, the GG genotype at rs2301436 in donors was associated with a higher incidence of invasive fungal disease at day 100 after HSCT (OR: 3.59; P = .008). 21763254 2011
Chronic graft-versus-host disease
CUI: C0867389
Disease: Chronic graft-versus-host disease
0.010 GeneticVariation BEFREE In multivariate analysis, patients receiving a transplant from a homozygous rs2301436 G allele donor showed less cGVHD (odds ratio [OR]: 0.16; P = .002), as was the case for a homozygous donor rs3093023 G allele (OR: 0.24; P = .005). 21763254 2011