|
Lupus Erythematosus, Systemic
|
|
0.840 |
GeneticVariation
|
GWASCAT |
Transancestral mapping and genetic load in systemic lupus erythematosus.
|
28714469 |
2017 |
|
Lupus Erythematosus, Systemic
|
|
0.840 |
GeneticVariation
|
BEFREE |
This replication effort confirmed five reported SLE susceptibility loci reaching genome-wide levels of significance (P(meta) <5.00 × 10(-08)): TNFSF4 (rs1418190, odds ratio (OR) = 0.81, P(meta) = 1.08 × 10(-08); rs4916219, OR = 0.80, P(meta )= 7.77 × 10(-09)), IRF8 (rs2934498, OR = 1.25, P(meta) = 4.97 × 10(-09)), miR-146a (rs2431697, OR = 0.69, P(meta) = 1.15 × 10(-22)), CD44 (rs2732547, OR = 0.82, P(meta) = 1.55 × 10(-11)), and TMEM39A (rs12494314, OR = 0.84, P(meta) = 1.01 × 10(-09)).
|
25890262 |
2015 |
|
Lupus Erythematosus, Systemic
|
|
0.840 |
GeneticVariation
|
GWASCAT |
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
|
26502338 |
2015 |
|
Lupus Erythematosus, Systemic
|
|
0.840 |
GeneticVariation
|
BEFREE |
The results from our case-control study and the meta-analyses indicate that rs2431697 T allele significantly associates with the increased risk of systemic lupus erythematosus.
|
26251230 |
2015 |
|
Lupus Erythematosus, Systemic
|
|
0.840 |
GeneticVariation
|
BEFREE |
The results of our meta-analysis suggest that miR-146a rs57095329 and rs2431697 SNPs are associated with SLE susceptibility.
|
24803388 |
2014 |
|
Lupus Erythematosus, Systemic
|
|
0.840 |
GeneticVariation
|
BEFREE |
Of the three variants analyzed, only rs2431697 was genetically associated with SLE in Europeans.
|
22218224 |
2012 |
|
Lupus Erythematosus, Systemic
|
|
0.840 |
GeneticVariation
|
GWASDB |
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
|
18204446 |
2008 |
|
Multiple Sclerosis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
|
Psoriasis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Association analyses identify six new psoriasis susceptibility loci in the Chinese population.
|
20953187 |
2010 |
|
Atrial Fibrillation
|
|
0.020 |
GeneticVariation
|
BEFREE |
We reported that rs2431697 of miR-146a, a negative regulator of inflammation, predicts ACEs in patients with AF.
|
29437577 |
2018 |
|
Atrial Fibrillation
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our study established MIR146A rs2431697 as a prognostic biomarker for ACE in anticoagulated AF patients.
|
25008481 |
2014 |
|
Juvenile rheumatoid arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
These findings did not support the genetic association between miR-146a rs2910164 (G/C) and JRA susceptibility, as well as the association of miR-196a-2 rs11614913 (C/T), miR-146a rs2431697, miR-146a rs57095329, miR-149 rs22928323 with arthritis.
|
31235484 |
2019 |
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, we found that the T allele of rs2431697</span> was a risk factor of CAD in the Chinese population.
|
28489066 |
2017 |
|
Coronary heart disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two Single Nucleotide Polymorphisms (rs2431697 and rs2910164) of miR-146a Are Associated with Risk of Coronary Artery Disease.
|
28489066 |
2017 |
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two Single Nucleotide Polymorphisms (rs2431697 and rs2910164) of miR-146a Are Associated with Risk of Coronary Artery Disease.
|
28489066 |
2017 |
|
Autoimmune Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The miR-146a SNPs rs2910164, rs57095329, rs2431697 are associated with susceptibility to certain autoimmune diseases.
|
27098222 |
2016 |
|
Pituitary Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
rs2431697 is located on 5q33.3, between pituitary tumor-transforming gene 1 and miR-146a.
|
26251230 |
2015 |