rs2647087, None

N. diseases: 2
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Pancreatitis
CUI: C0030305
Disease: Pancreatitis
0.020 GeneticVariation BEFREE The class II HLA region (at rs2647087) is an important marker of AZA-induced pancreatitis risk. 29270995 2018
Pancreatitis
CUI: C0030305
Disease: Pancreatitis
0.020 GeneticVariation BEFREE Patients heterozygous at rs2647087 have a 9% risk of developing pancreatitis after administration of a thiopurine, whereas homozygotes have a 17% risk. 25217962 2014
Inflammatory Bowel Diseases
CUI: C0021390
Disease: Inflammatory Bowel Diseases
0.010 GeneticVariation BEFREE We propose a simple and clinically implementable algorithm based on rs2647087 and TPMT genotypes for AZA selection and dosing for patients with IBD. 29270995 2018