|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.
|
26895986 |
2016 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.
|
26895986 |
2016 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Nucleosome positioning is unaltered at MLH1 splice site mutations in cells derived from Lynch syndrome patients.
|
25530820 |
2014 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families.
|
20937110 |
2010 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
Screening of the DNA mismatch repair genes MLH1, MSH2 and MSH6 in a Greek cohort of Lynch syndrome suspected families.
|
20937110 |
2010 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Systematic mRNA analysis for the effect of MLH1 and MSH2 missense and silent mutations on aberrant splicing.
|
16395668 |
2006 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
Systematic mRNA analysis for the effect of MLH1 and MSH2 missense and silent mutations on aberrant splicing.
|
16395668 |
2006 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
Systematic mRNA analysis for the effect of MLH1 and MSH2 missense and silent mutations on aberrant splicing.
|
16395668 |
2006 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer.
|
17054581 |
2006 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer).
|
15872200 |
2005 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer.
|
15849733 |
2005 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer.
|
15713769 |
2005 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
Hereditary non-polyposis colorectal cancer: clinical and molecular evidence for a new entity of hereditary colorectal cancer.
|
15955785 |
2005 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer.
|
15849733 |
2005 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.
|
12658575 |
2003 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
Functional analysis of hMLH1 variants and HNPCC-related mutations using a human expression system.
|
11781295 |
2002 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.
|
11524701 |
2001 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.
|
11524701 |
2001 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.
|
11524701 |
2001 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
Characterization of MLH1 and MSH2 alternative splicing and its relevance to molecular testing of colorectal cancer susceptibility.
|
9490293 |
1998 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
CausalMutation
|
CLINVAR |
Germline mutations of hMLH1 and hMSH2 genes in Korean hereditary nonpolyposis colorectal cancer.
|
8797773 |
1996 |
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
Alternative splicing of MLH1 messenger RNA in human normal cells.
|
7728749 |
1995 |
|
Hereditary Nonpolyposis Colorectal Cancer
|
|
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|