|
AUTISM, SUSCEPTIBILITY TO, 15
|
|
0.700 |
SusceptibilityMutation
|
CLINVAR |
|
|
|
|
Autism Spectrum Disorders
|
|
0.030 |
GeneticVariation
|
BEFREE |
In the updated meta-analysis, the association between the two frequently reported SNPs (rs2710102 and rs7794745) in CNTNAP2 and the risk of ASD was explored.
|
30681286 |
2019 |
|
Autism Spectrum Disorders
|
|
0.030 |
GeneticVariation
|
BEFREE |
We analyzed the SNPs (rs7794745 and rs2710102) in the CNTNAP2 gene of 210 individuals with idiopathic ASD and 200 non-autistic individuals by polymerase chain reaction-restriction fragment length polymorphism.
|
26909962 |
2016 |
|
Autism Spectrum Disorders
|
|
0.030 |
GeneticVariation
|
BEFREE |
Although association was found with rs2710102, the risk allele (a) for the traits studied here is the nonrisk allele for ASD and specific language impairment.
|
21193173 |
2011 |
|
Autistic Disorder
|
|
0.020 |
GeneticVariation
|
BEFREE |
Furthermore, we failed to replicate in our sample a previous association finding of two single nucleotide polymorphisms (rs2710102 and rs7794745) in the CNTNAP2 gene with autism.
|
23277129 |
2013 |
|
Autistic Disorder
|
|
0.020 |
GeneticVariation
|
BEFREE |
In the current study we investigated the functional effects of variants of CNTNAP2 associated with autism and language impairment (rs7794745 and rs2710102; presumed risk alleles T and C, respectively) in healthy individuals using functional magnetic resonance imaging (fMRI) during performance of a language task (n = 66).
|
21987501 |
2011 |
|
Mental disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association of proposed functional SNPs rs7794745 and rs2710102, reported to influence brain connectivity, was not replicated; nor did predicted functional SNPs yield significant results in meta-analysis across psychiatric disorders at either SNP-level or gene-level.
|
30586385 |
2018 |
|
Abnormal behavior
|
|
0.010 |
GeneticVariation
|
BEFREE |
The association of proposed functional SNPs rs7794745 and rs2710102, reported to influence brain connectivity, was not replicated; nor did predicted functional SNPs yield significant results in meta-analysis across psychiatric disorders at either SNP-level or gene-level.
|
30586385 |
2018 |
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that the genotypes of rs17236239 were significantly associated with schizophrenia and the alleles of rs2710102 and rs2710117 were significantly associated with major depression.
|
23123147 |
2013 |
|
Unipolar Depression
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that the genotypes of rs17236239 were significantly associated with schizophrenia and the alleles of rs2710102 and rs2710117 were significantly associated with major depression.
|
23123147 |
2013 |
|
Schizophrenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that the genotypes of rs17236239 were significantly associated with schizophrenia and the alleles of rs2710102 and rs2710117 were significantly associated with major depression.
|
23123147 |
2013 |
|
Language Disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the current study we investigated the functional effects of variants of CNTNAP2 associated with autism and language impairment (rs7794745 and rs2710102; presumed risk alleles T and C, respectively) in healthy individuals using functional magnetic resonance imaging (fMRI) during performance of a language task (n = 66).
|
21987501 |
2011 |
|
Specific language impairment
|
|
0.010 |
GeneticVariation
|
BEFREE |
Although association was found with rs2710102, the risk allele (a) for the traits studied here is the nonrisk allele for ASD and specific language impairment.
|
21193173 |
2011 |
|
Selective mutism specific to childhood and adolescence
|
|
0.010 |
GeneticVariation
|
BEFREE |
Analyses revealed nominal significance (p = .018) for association of SM with rs2710102, which, with rs6944808, was part of a common haplotype associated with SM (permutation p = .022).
|
21193173 |
2011 |
|
Selective Mutism
|
|
0.010 |
GeneticVariation
|
BEFREE |
Analyses revealed nominal significance (p = .018) for association of SM with rs2710102, which, with rs6944808, was part of a common haplotype associated with SM (permutation p = .022).
|
21193173 |
2011 |