|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
Numerous studies have addressed the association of a functional insertion (I)/deletion (D) polymorphism (-94ins/delATTG, rs28362491) in the promoter region of NFKB1 gene with the risk of various types of cancer; however, their conclusions have been inconsistent.
|
28039461 |
2017 |
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
The 94ins/del ATTG (rs28362491) polymorphism located in the NFKB1 gene has been associated to various cancers and the ATTG2/ATTG2 genotype was correlated to melanoma risk in Sweden.
|
27145040 |
2016 |
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion ATTG polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to affect NF-KB1 expression and confer susceptibility to different types of cancer.
|
26835711 |
2016 |
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NF-κ B1 gene was reported to influence NF-κ B1 expression and confer susceptibility to different types of cancer.
|
26484607 |
2016 |
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to influence NFKB1 expression and confer susceptibility to different types of cancer.
|
23977085 |
2013 |
|
Malignant Neoplasms
|
|
0.060 |
GeneticVariation
|
BEFREE |
Recently, a common insertion/deletion (-94insertion/deletion ATTG, rs28362491) polymorphism in the NFkappaB1 promoter region has been extensively investigated for association with cancer risk but the results have been inconsistent.
|
22320942 |
2011 |
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
Numerous studies have addressed the association of a functional insertion (I)/deletion (D) polymorphism (-94ins/delATTG, rs28362491) in the promoter region of NFKB1 gene with the risk of various types of cancer; however, their conclusions have been inconsistent.
|
28039461 |
2017 |
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NF-κ B1 gene was reported to influence NF-κ B1 expression and confer susceptibility to different types of cancer.
|
26484607 |
2016 |
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion ATTG polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to affect NF-KB1 expression and confer susceptibility to different types of cancer.
|
26835711 |
2016 |
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NFKB1 gene was reported to influence NFKB1 expression and confer susceptibility to different types of cancer.
|
23977085 |
2013 |
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
Recently, a common insertion/deletion (-94insertion/deletion ATTG, rs28362491) polymorphism in the NFkappaB1 promoter region has been extensively investigated for association with cancer risk but the results have been inconsistent.
|
22320942 |
2011 |
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
The genotype and allele frequencies of the rs28362491 (promoter region) polymorphism in the CAD patients were significantly different from those in the healthy controls.
|
27525877 |
2016 |
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
Association Between the NFKB1-94ins/del ATTG Polymorphism (rs28362491) and Coronary Artery Disease: A Systematic Review and Meta-Analysis.
|
26799199 |
2016 |
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
Significant difference in the frequency of genotypes (P = 0.001) and alleles (P = 0.001) of rs28362491</span> polymorphism was observed in CAD cases compared to controls.
|
26075620 |
2015 |
|
Coronary Artery Disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
The DD genotype of the SNP (rs28362491) in the NFKB1 gene may be considered a genetic marker of CAD in Han and Uygur women in China.
|
24818816 |
2014 |
|
Hepatitis C
|
|
0.030 |
GeneticVariation
|
BEFREE |
Besides normal routine laboratory testing for HCV, patients' sera were evaluated also for retinol, retinol-binding protein 4 and the following SNPs: PNPLA3 (rs738409), TM6SF2 (rs58542926), MBOAT7 (rs641738), IL28B (rs12979860), TIMP-1 (rs4898), TIMP-2 (rs8179090), NF-kB promoter (rs28362491).
|
31826071 |
2019 |
|
Hepatitis C
|
|
0.030 |
GeneticVariation
|
BEFREE |
NFKB1 rs28362491-D allele was functionally associated with the increased risk of susceptibility to HCV infection in the Chinese Han population.
|
30056167 |
2018 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
One of these markers (rs28362491) and the marker in the <i>UGT1A1</i> gene (rs8175347) were positively associated with the development of CRC.
|
29358861 |
2017 |
|
Hepatitis C
|
|
0.030 |
GeneticVariation
|
BEFREE |
The present study aims to evaluate the association between -94Ins/DelATTG (rs28362491) polymorphism in NF-κB1 gene promoter region and 2758G>A (rs696) single nucleotide polymorphism in the 3'UTR region of NFκBIA and the outcomes of HCV infection.
|
26827631 |
2016 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Del-carriers of the NFKB1/rs28362491 polymorphism had a 17% (95%CI: 1.03-1.34; P = 0.02) increased risk of CRC compared to homozygous carriers of the ins-allele.
|
25705893 |
2015 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
The variant allele of NFKB1 -94 ins/del ATTG (rs28362491) polymorphism is associated with higher risk of sporadic CRC in Malaysian population.
|
23806437 |
2013 |
|
Nasopharyngeal carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
rs28362491 polymorphism was significantly associated with the risk of HNCs, especially with NC.
|
31612070 |
2019 |
|
Malignant neoplasm of breast
|
|
0.020 |
GeneticVariation
|
BEFREE |
Gene Combination of CD44 rs187116, CD133 rs2240688, NF-κB1 rs28362491 and GSTM1 Deletion as a Potential Biomarker in Risk Prediction of Breast Cancer in Lower Northern Thailand.
|
31450925 |
2019 |
|
Lip and Oral Cavity Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In subgroup analyses, the rs28362491 polymorphism was associated with the risk of nasopharyngeal carcinoma (NC), but not with oral cancer (OC).
|
31612070 |
2019 |
|
Malignant neoplasm of mouth
|
|
0.020 |
GeneticVariation
|
BEFREE |
In subgroup analyses, the rs28362491 polymorphism was associated with the risk of nasopharyngeal carcinoma (NC), but not with oral cancer (OC).
|
31612070 |
2019 |