rs2853676, TERT

N. diseases: 29
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Lung Diseases, Interstitial
CUI: C0206062
Disease: Lung Diseases, Interstitial
0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. 23583980 2013
Astrocytoma
CUI: C0004114
Disease: Astrocytoma
0.010 GeneticVariation BEFREE In the additive model, all three tSNPs (rs2297440, rs2853676, and rs6010620) were associated with increased astrocytoma risk. 23812731 2013
Childhood Astrocytoma
CUI: C4086152
Disease: Childhood Astrocytoma
0.010 GeneticVariation BEFREE In the additive model, all three tSNPs (rs2297440, rs2853676, and rs6010620) were associated with increased astrocytoma risk. 23812731 2013
Glioma
CUI: C0017638
Disease: Glioma
0.840 GeneticVariation BEFREE The genotype #GA# for rs1695 was recognized to be a protective genotype for glioma (OR, 0.67; 95% CI, 0.47-0.96; P = 0.027), while the genotype #AG# for rs2853676 was shown to be a risk genotype for glioma (OR, 1.50; 95% CI, 1.05-2.15; P = 0.025). 22795327 2012
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.020 GeneticVariation BEFREE Mean RTL at age 60 was associated with four genetic variants of the hTERT gene (rs2736100, rs2853672, rs2853677, and rs2853676), two of which reported to be associated with cancer risk. 22539396 2012
Primary malignant neoplasm
CUI: C1306459
Disease: Primary malignant neoplasm
0.020 GeneticVariation BEFREE Mean RTL at age 60 was associated with four genetic variants of the hTERT gene (rs2736100, rs2853672, rs2853677, and rs2853676), two of which reported to be associated with cancer risk. 22539396 2012
Glioma
CUI: C0017638
Disease: Glioma
0.840 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791 2011
melanoma
CUI: C0025202
Disease: melanoma
0.010 GeneticVariation BEFREE After correction for multiple testing within each gene, two SNPs in the TERT gene (rs2853676 and rs2242652) and one SNP in the TRF1 gene (rs2981096) showed significant associations with the risk of melanoma. 21116649 2011
Nasopharyngeal carcinoma
CUI: C2931822
Disease: Nasopharyngeal carcinoma
0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145 2010
Malignant Testicular Germ Cell Tumor
CUI: C0855197
Disease: Malignant Testicular Germ Cell Tumor
0.700 GeneticVariation GWASDB Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer. 20543847 2010
Glioma
CUI: C0017638
Disease: Glioma
0.840 GeneticVariation GWASDB Genome-wide association study identifies five susceptibility loci for glioma. 19578367 2009
Glioma
CUI: C0017638
Disease: Glioma
0.840 GeneticVariation GWASCAT Genome-wide association study identifies five susceptibility loci for glioma. 19578367 2009
Central Nervous System Neoplasms
CUI: C0085136
Disease: Central Nervous System Neoplasms
0.700 GeneticVariation GWASCAT Genome-wide association study identifies five susceptibility loci for glioma. 19578367 2009