|
Glioma
|
|
0.840 |
GeneticVariation
|
BEFREE |
Univariate analyses showed that ACYP2 rs12615793 and TERT rs2853676 loci affected progression-free survival in glioma patients; both ZNF208 rs8105767 and ACYP2 rs843720 affected the OS of patients with low-grade gliomas.
|
28985021 |
2017 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
BEFREE |
Our study indicates that TERT rs2853676 polymorphisms correlate with glioma survival and recurrence rates in a Chinese population, which suggests that they could potentially serve as prognostic markers in glioma patients.
|
27655710 |
2016 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that the TERT genetic polymorphism rs2853676 is associated with increased risk of glioma, lung adenocarcinoma and ovarian cancer among Caucasians.
|
26042809 |
2015 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
BEFREE |
The genotype #GA# for rs1695 was recognized to be a protective genotype for glioma (OR, 0.67; 95% CI, 0.47-0.96; P = 0.027), while the genotype #AG# for rs2853676 was shown to be a risk genotype for glioma (OR, 1.50; 95% CI, 1.05-2.15; P = 0.025).
|
22795327 |
2012 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
GWASDB |
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
|
21531791 |
2011 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five susceptibility loci for glioma.
|
19578367 |
2009 |
|
Glioma
|
|
0.840 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies five susceptibility loci for glioma.
|
19578367 |
2009 |
|
Plexiform leiomyoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.
|
31649266 |
2019 |
|
Uterine Fibroids
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.
|
31649266 |
2019 |
|
Lung Diseases, Interstitial
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.
|
23583980 |
2013 |
|
Nasopharyngeal carcinoma
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
|
20512145 |
2010 |
|
Malignant Testicular Germ Cell Tumor
|
|
0.700 |
GeneticVariation
|
GWASDB |
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.
|
20543847 |
2010 |
|
Central Nervous System Neoplasms
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies five susceptibility loci for glioma.
|
19578367 |
2009 |
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
A significant association between TERT rs2853676 allele A and cancer susceptibility was demonstrated under a per-allele risk analysis (OR = 1.08, 95% CI = 1.04-1.13).
|
26042809 |
2015 |
|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
A significant association between TERT rs2853676 allele A and cancer susceptibility was demonstrated under a per-allele risk analysis (OR = 1.08, 95% CI = 1.04-1.13).
|
26042809 |
2015 |
|
Adenocarcinoma of lung (disorder)
|
|
0.020 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that the TERT genetic polymorphism rs2853676 is associated with increased risk of glioma, lung adenocarcinoma and ovarian cancer among Caucasians.
|
26042809 |
2015 |
|
Adenocarcinoma of lung (disorder)
|
|
0.020 |
GeneticVariation
|
BEFREE |
Gene variations rs2736100 and rs2853676 in TERT and rs401681 and rs31489 in CLPTM1L had significant direct associations on lung adenocarcinoma without indirect effects through nicotine dependence.
|
25233467 |
2014 |
|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Mean RTL at age 60 was associated with four genetic variants of the hTERT gene (rs2736100, rs2853672, rs2853677, and rs2853676), two of which reported to be associated with cancer risk.
|
22539396 |
2012 |
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
Mean RTL at age 60 was associated with four genetic variants of the hTERT gene (rs2736100, rs2853672, rs2853677, and rs2853676), two of which reported to be associated with cancer risk.
|
22539396 |
2012 |
|
Malignant neoplasm of breast
|
|
0.010 |
GeneticVariation
|
BEFREE |
The variants rs10069690 and rs2853676 were also described as risk factors for BC.
|
29332343 |
2019 |
|
Chronic Obstructive Airway Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs2853676 in TERT could increase the risk of COPD in the dominant model ("C/T-T/T" genotype, p = 0.026) and in the Log-additive model (p = 0.022).
|
31270965 |
2019 |
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The variants rs10069690 and rs2853676 were also described as risk factors for BC.
|
29332343 |
2019 |
|
Giant Cell Arteritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We observed that CXCR4 rs6430612, TERT rs10069690, and rs2853676 as well as VPS34 rs2162440 are significantly associated with GCA development.
|
30900102 |
2019 |
|
Idiopathic Pulmonary Fibrosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The minor allele frequencies (MAF) were significantly greater for MUC5B rs868903 (P = 0.042) and TERT rs2853676 (P = 0.041) in IPF than those in healthy controls.
|
31653936 |
2019 |
|
MYOTONIC DYSTROPHY 1
|
|
0.010 |
GeneticVariation
|
BEFREE |
Chinese polymyositis (PM) patients (n =291), dermatomyositis (DM) patients (n=526) and ethnically-matched healthy controls (n =968) were genotyped for the CCL21 region SNPs (rs951005 and rs2492358), ERBB3 (rs2292239 and rs11171739), and TERT (rs2853676 and rs10069690), by using the Sequenom MassArray system.
|
26320593 |
2015 |