rs2867125, None

N. diseases: 8
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Finding of body mass index
CUI: C0578022
Disease: Finding of body mass index
0.800 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
Body mass index procedure
CUI: C0005893
Disease: Body mass index procedure
0.800 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
Body mass index procedure
CUI: C0005893
Disease: Body mass index procedure
0.800 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
Finding of body mass index
CUI: C0578022
Disease: Finding of body mass index
0.800 GeneticVariation GWASDB Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. 23001569 2013
Finding of body mass index
CUI: C0578022
Disease: Finding of body mass index
0.800 GeneticVariation GWASDB Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
Body mass index procedure
CUI: C0005893
Disease: Body mass index procedure
0.800 GeneticVariation GWASDB Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458 2018
Physical Activity Measurement
CUI: C4049938
Disease: Physical Activity Measurement
0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590 2017
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500 2017
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
Body mass index
CUI: C1305855
Disease: Body mass index
0.700 GeneticVariation GWASCAT Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630 2010
Smoking Behaviors
CUI: C1519383
Disease: Smoking Behaviors
0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888 2010
Obesity
CUI: C0028754
Disease: Obesity
0.020 GeneticVariation BEFREE Eight loci, rs10968576 (BDNF), rs3817334 (MTCH2), rs1558902 (FTO), rs571312 (MC4R), rs543874 (SEC16B), rs987237 (TFAP2B), rs2867125 (TMEM18) and rs7138803 (FAIM2), were previously known obesity susceptibility loci, and the remaining four loci, rs1514175 (TNNI3K), rs206936 (NUDT3), rs4771122 (MTIF3) and rs2241423 (MAP2K5), were newly identified as BMI loci by the GIANT study. 22041983 2012
Obesity
CUI: C0028754
Disease: Obesity
0.020 GeneticVariation BEFREE The SNP rs10913469 in SEC16B (P=0.000012) and four SNPs (rs2867125, rs6548238, rs4854344 and rs7561317) in the TMEM18 gene (P=0.00015), all of which were in almost absolute linkage disequilibrium, were significantly associated with obesity in the Japanese population. 19851340 2009
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.010 GeneticVariation BEFREE A significant association between BMI and the risk of stroke is observed; however, the sensitivity analyses suggest that the association is attributed to the potential pleiotropic effects of rs2867125 and rs1558902. 28964830 2018