Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Obsessive-Compulsive Disorder
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
0.060 GeneticVariation BEFREE In the present study, we aimed to assess the association of SLC1A1 polymorphisms (rs301430, rs2228622 and rs3780413) with OCD and its clinical characteristics, as well as the importance of these SNPs in the response of OCD patients to SSRI pharmacotherapy. 30315580 2019
Obsessive-Compulsive Disorder
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
0.060 GeneticVariation BEFREE The C-T-G haplotype at rs301430-rs301434-rs3087879 of SLC1A1 was significantly associated with higher PD scores after adjusted for age, sex, and OCD status. 29304071 2018
Obsessive-Compulsive Disorder
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
0.060 GeneticVariation BEFREE This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese. 23411042 2013
Obsessive-Compulsive Disorder
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
0.060 GeneticVariation BEFREE Two haplotypes at 3 SNPs, rs3087879, rs301430, and rs7858819, were significantly associated with OCD after multiple-testing correction and contained 2 SNPs associated with expression levels. 19349310 2009
Obsessive-Compulsive Disorder
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
0.060 GeneticVariation BEFREE Additionally, an rs301430-rs301979 haplotype identified for OCD was investigated. 19360657 2008
Obsessive-Compulsive Disorder
CUI: C0028768
Disease: Obsessive-Compulsive Disorder
0.060 GeneticVariation BEFREE Association between OCD and the three-marker haplotype rs12682807/ rs2072657/ rs301430, with overtransmission of A/T/T, was observed in both genders combined (global P = 0.0015) and in males (global P = 0.0031). 17894418 2007
Autism Spectrum Disorders
CUI: C1510586
Disease: Autism Spectrum Disorders
0.010 GeneticVariation BEFREE Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. 20155310 2010
Obsessive compulsive behavior
CUI: C0600104
Disease: Obsessive compulsive behavior
0.010 GeneticVariation BEFREE Investigated association of single nucleotide polymorphism (SNP) rs301430 in glutamate transporter gene (SLC1A1) with severity of repetitive behaviors (obsessive-compulsive behaviors, tics) and anxiety in children with autism spectrum disorder (ASD). 20155310 2010
Anxiety Disorders
CUI: C0003469
Disease: Anxiety Disorders
0.010 GeneticVariation BEFREE Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. 20155310 2010
Anxiety
CUI: C0003467
Disease: Anxiety
0.010 GeneticVariation BEFREE Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. 20155310 2010
Pervasive Development Disorder
CUI: C0524528
Disease: Pervasive Development Disorder
0.010 GeneticVariation BEFREE Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder. 20155310 2010
Autistic Disorder
CUI: C0004352
Disease: Autistic Disorder
0.010 GeneticVariation BEFREE To test for association between SLC1A1 and autism, we typed three single nucleotide polymorphisms (SNPs, rs301430, rs301979, rs301434) previously associated with OCD in 86 strictly defined trios with autism. 19360657 2008