rs35054928, FGFR2

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.710 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.710 GeneticVariation BEFREE We confirmed ten risk-associated variants within three reported breast cancer susceptibility loci in a Chinese Han population: 5q11.2 (rs16886181, P = 5.29 × 10(-6), OR = 1.19; rs1017226, P = 5.24 × 10(-4), OR = 1.22; rs16886034, P = 2.00 × 10(-3), OR = 1.21; rs16886113, P = 1.24 × 10(-3), OR = 1.20; rs16886364, P = 9.20 × 10(-4), OR = 1.21; rs16886397, P = 1.17 × 10(-3), OR = 1.20; rs16886448, P = 1.62 × 10(-3,)OR = 1.20; and rs2229882, P = 5.14 × 10(-4), OR = 1.31), 5q14.3 (rs421379, P = 2.83 × 10(-13), OR = 1.83), and 10q26.1 (rs35054928, P = 7.73 × 10(-6), OR = 1.18). 27572337 2016
Luminal B Breast Carcinoma
CUI: C3642346
Disease: Luminal B Breast Carcinoma
0.010 GeneticVariation BEFREE Through a stratification analysis, <i>5q11.2/MAP3K1</i> (rs16886034, rs16886364, rs16886397, rs1017226, rs16886448) and <i>7q32.3/LINC-PINT</i> (rs4593472) were associated with Luminal A, and <i>10q26.1/FGFR2</i> (rs35054928) was associated with Luminal B. 28408616 2017
Luminal A Breast Carcinoma
CUI: C3642345
Disease: Luminal A Breast Carcinoma
0.010 GeneticVariation BEFREE Through a stratification analysis, <i>5q11.2/MAP3K1</i> (rs16886034, rs16886364, rs16886397, rs1017226, rs16886448) and <i>7q32.3/LINC-PINT</i> (rs4593472) were associated with Luminal A, and <i>10q26.1/FGFR2</i> (rs35054928) was associated with Luminal B. 28408616 2017
Malignant neoplasm of breast
CUI: C0006142
Disease: Malignant neoplasm of breast
0.010 GeneticVariation BEFREE We confirmed ten risk-associated variants within three reported breast cancer susceptibility loci in a Chinese Han population: 5q11.2 (rs16886181, P = 5.29 × 10(-6), OR = 1.19; rs1017226, P = 5.24 × 10(-4), OR = 1.22; rs16886034, P = 2.00 × 10(-3), OR = 1.21; rs16886113, P = 1.24 × 10(-3), OR = 1.20; rs16886364, P = 9.20 × 10(-4), OR = 1.21; rs16886397, P = 1.17 × 10(-3), OR = 1.20; rs16886448, P = 1.62 × 10(-3,)OR = 1.20; and rs2229882, P = 5.14 × 10(-4), OR = 1.31), 5q14.3 (rs421379, P = 2.83 × 10(-13), OR = 1.83), and 10q26.1 (rs35054928, P = 7.73 × 10(-6), OR = 1.18). 27572337 2016