|
Myocardial Infarction
|
|
0.820 |
GeneticVariation
|
BEFREE |
Since inflammation-related single-nucleotide polymorphism (SNP (rs3782886)) is reportedly associated with myocardial infarction and short stature, rs3782886 could be associated with a high platelet count and thus more intense endothelial repair activity.
|
31043174 |
2019 |
|
Myocardial Infarction
|
|
0.820 |
GeneticVariation
|
BEFREE |
Asian-specific single nucleotide polymorphism (SNPs) (rs3782886) is reported to be associated with myocardial infarction; sarcopenia is reported to be associated with coronary subclinical atherosclerosis.
|
29165153 |
2017 |
|
Myocardial Infarction
|
|
0.820 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
|
24916648 |
2015 |
|
Myocardial Infarction
|
|
0.820 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese.
|
24916648 |
2015 |
|
Myocardial Infarction
|
|
0.820 |
GeneticVariation
|
GWASDB |
SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
|
21107343 |
2011 |
|
Uric acid measurement (procedure)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
Folic acid measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Surprisingly, we discovered three novel loci rs3782886, rs671, and rs4646776 of ALDH2 gene were suggestively significantly associated with folate serum folate levels in the male population studied (P = 2.17 × 10<sup>-7</sup>, P = 3.60 × 10<sup>-7</sup>, P = 3.99 × 10<sup>-7</sup>, respectively) after adjusting for population stratification, BMI and age.
|
29953918 |
2018 |
|
Alcoholic Intoxication, Chronic
|
|
0.700 |
GeneticVariation
|
GWASDB |
"ALDH2 is associated to alcohol dependence and is the major genetic determinant of ""daily maximum drinks"" in a GWAS study of an isolated rural Chinese sample."
|
24277619 |
2014 |
|
Coronary heart disease
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of a coronary artery disease risk variant.
|
23364394 |
2013 |
|
Alcohol consumption
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.
|
23555315 |
2013 |
|
Drinking behavior processes
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common variants at 12q24 are associated with drinking behavior in Han Chinese.
|
23364009 |
2013 |
|
Coronary heart disease
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary artery disease in the Japanese.
|
21971053 |
2012 |
|
Hepatitis B
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
|
21750111 |
2011 |
|
Malignant neoplasm of esophagus
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.
|
21642993 |
2011 |
|
Drinking behavior processes
|
|
0.700 |
GeneticVariation
|
GWASDB |
Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population.
|
21372407 |
2011 |
|
Alanine aminotransferase measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
20139978 |
2010 |
|
Serum Alanine Aminotransferase Measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
20139978 |
2010 |
|
Dwarfism
|
|
0.020 |
GeneticVariation
|
BEFREE |
SNP (rs3782886) was shown to be associated with high platelet count and short stature.
|
31043174 |
2019 |
|
Dwarfism
|
|
0.020 |
GeneticVariation
|
BEFREE |
We also found that independent of known cardiovascular risk factors, with the non-minor homo of rs3782886 taken as the reference group, the adjusted OR and 95% CI for short stature and reduced MTP of the minor homo allele were 3.06 (1.23, 7.63) and 3.26 (1.33, 8.03), respectively.
|
29165153 |
2017 |
|
Overweight and obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
The major allele of rs696217 significantly increased BMI and an increased OR with obesity, while the minor allele of rs3782886 was associated with significantly decreased AC and the decreased ORs with overweight and obesity.
|
27245511 |
2019 |
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
High platelet counts were found to be independently and positively associated with hypertension while rs3782886 was independently associated with high platelet levels and short stature.
|
31043174 |
2019 |
|
Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
The major allele of rs696217 significantly increased BMI and an increased OR with obesity, while the minor allele of rs3782886 was associated with significantly decreased AC and the decreased ORs with overweight and obesity.
|
27245511 |
2019 |
|
Chronic Kidney Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
After adjustment for clinical factors, kidney function was associated with BRAP rs3782886 and SPATA5L1 rs2467853 and the GRS for CKD that we developed was associated CKD.
|
29016630 |
2017 |
|
Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Asian-specific single nucleotide polymorphism (SNPs) (rs3782886) is reported to be associated with myocardial infarction; sarcopenia is reported to be associated with coronary subclinical atherosclerosis.
|
29165153 |
2017 |
|
Sarcopenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, no studies have reported on the association between sa</span>rcopenia and short stature nor on the impact of rs3782886 on this association.
|
29165153 |
2017 |