|
Epilepsy
|
|
0.060 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that SCN1A rs3</span>812718 polymorphism is associated with the risk of epilepsy.
|
29605548 |
2018 |
|
Epilepsy
|
|
0.060 |
GeneticVariation
|
BEFREE |
Association between SCN1A polymorphism rs3812718 and valproic acid resistance in epilepsy children: a case-control study and meta-analysis.
|
30413604 |
2018 |
|
Epilepsy
|
|
0.060 |
GeneticVariation
|
BEFREE |
Interaction between rs12912233-rs880626 and rs3812718 was associated with the epilepsy risk in the subjects overall (p=0.001).
|
25668517 |
2015 |
|
Epilepsy
|
|
0.060 |
GeneticVariation
|
BEFREE |
The strongest association with epilepsy was rs3812718, or SCN1A IVS5N+5G>A: odds ratio (OR) = 0.85 for allele G (p = 0.0009) and 0.73 for genotype GG versus AA (p = 0.003).
|
24337656 |
2014 |
|
Epilepsy
|
|
0.060 |
GeneticVariation
|
BEFREE |
SCN1A rs3812718 polymorphism and susceptibility to epilepsy with febrile seizures: a meta-analysis.
|
24076350 |
2014 |
|
Epilepsy
|
|
0.060 |
GeneticVariation
|
BEFREE |
A common SCN1A IVS5-91G>A (rs3812718) allele has been attributed to be a possible modifying factor for epilepsy susceptibility and therapeutic response.
|
23466530 |
2013 |
|
Febrile Convulsions
|
|
0.030 |
GeneticVariation
|
BEFREE |
SCN1A rs3812718 polymorphism and susceptibility to epilepsy with febrile seizures: a meta-analysis.
|
24076350 |
2014 |
|
Febrile Convulsions
|
|
0.030 |
GeneticVariation
|
BEFREE |
We conclude that in the population studied, although rs3812718 polymorphism increases the susceptibility to MTLE-HS, this is not by increasing the susceptibility to FS.
|
22578703 |
2012 |
|
Febrile Convulsions
|
|
0.030 |
GeneticVariation
|
BEFREE |
Arecent study in Caucasians found an association between the single nucleotide polymorphism (SNP) of SCN1A, IVS5N +5 G>A (rs3812718), and febrile seizures (FS).
|
20477842 |
2010 |
|
Drug Resistant Epilepsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Overall, our findings demonstrate an association of SCN1A IVS5-91 rs3812718 G>A polymorphism with AED responsiveness in monotherapy without evidence of an effect on drug-resistant epilepsy.
|
28144265 |
2017 |
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study validated gender-dependent association between genomic SCN1A rs3812718 polymorphism and TTR in CRC patients treated with adjuvant 5-FU-based chemotherapy.
|
23752739 |
2014 |
|
SPHEROCYTOSIS, TYPE 1 (disorder)
|
|
0.010 |
GeneticVariation
|
BEFREE |
While we observed no significant difference in allele and genotype frequencies of rs3812718 between MTLE-HS patients with and without FS, A allele and AA genotype were overrepresented in MTLE-HS patients when compared to controls.
|
22578703 |
2012 |
|
Epilepsy, Temporal Lobe
|
|
0.010 |
GeneticVariation
|
BEFREE |
Failure to find association between febrile seizures and SCN1A rs3812718 polymorphism in south Indian patients with mesial temporal lobe epilepsy and hippocampal sclerosis.
|
22578703 |
2012 |
|
Epilepsies, Partial
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results of the present study indicate that the rs3812718 SNP in the SCN1A gene is significantly associated with the retention rate of CBZ monotherapy in Chinese Han patients with focal epilepsy.
|
22292851 |
2012 |
|
Hippocampal sclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Failure to find association between febrile seizures and SCN1A rs3812718 polymorphism in south Indian patients with mesial temporal lobe epilepsy and hippocampal sclerosis.
|
22578703 |
2012 |