rs4416670, None

N. diseases: 7
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Vascular Endothelial Growth Factor Measurement
CUI: C2239222
Disease: Vascular Endothelial Growth Factor Measurement
0.700 GeneticVariation GWASDB Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels. 21757650 2011
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.010 GeneticVariation BEFREE We have investigated the association between 4 cis- and trans-genetic variants (rs6921438, rs4416670, rs6993770 and rs10738760) of the vascular endothelial growth factor (VEGF) gene and metabolic syndrome (MetS) and its individual components in an Iranian population. 29891039 2018
Depressed mood
CUI: C0344315
Disease: Depressed mood
0.010 GeneticVariation BEFREE The SNP rs4416670 was associated with increased risk for depression (OR: 1.60, P: 0.010). 28267147 2017
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.010 GeneticVariation BEFREE The SNP rs4416670 was associated with increased risk for depression (OR: 1.60, P: 0.010). 28267147 2017
Mental Depression
CUI: C0011570
Disease: Mental Depression
0.010 GeneticVariation BEFREE The SNP rs4416670 was associated with increased risk for depression (OR: 1.60, P: 0.010). 28267147 2017
Graves Disease
CUI: C0018213
Disease: Graves Disease
0.010 GeneticVariation BEFREE Whereas rs10738760 appeared specific to GD and FT3 production after six months of treatment, rs6921438 and rs4416670 were implicated in the risk for GD. 26955881 2016
Hyperthyroidism
CUI: C0020550
Disease: Hyperthyroidism
0.010 GeneticVariation BEFREE We also showed that the T allele of rs4416670 polymorphism was associated with increased risk of hyperthyroidism in patients treated for six months, independently of their initial diagnosis. 26955881 2016