|
Schizophrenia
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
|
Schizophrenia
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.
|
31268507 |
2019 |
|
Schizophrenia
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Schizophrenia
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of schizophrenia in Ashkenazi Jews.
|
26198764 |
2015 |
|
Schizophrenia
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Biological insights from 108 schizophrenia-associated genetic loci.
|
25056061 |
2014 |
|
Schizophrenia
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
|
23974872 |
2013 |
|
Schizophrenia
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
|
23974872 |
2013 |
|
Child Development Disorders, Pervasive
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Post-Traumatic Stress Disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
We also demonstrate that the SRR single nucleotide polymorphism, rs4523957, is associated with posttraumatic stress disorder in humans, consistent with the facilitatory effect of D-serine on fear extinction.
|
29025687 |
2018 |
|
Epilepsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Intriguingly, the activity of the SMG6 promoter with the mutant allele at rs4523957 decreased by 22% in the dual-luciferase assay, and up-regulated expression of SMG6 was observed in an epilepsy rat model.
|
29363864 |
2018 |
|
Epilepsy, Temporal Lobe
|
|
0.010 |
GeneticVariation
|
BEFREE |
In particular, variation at rs4523957 likely inhibits SMG6 transcription and plays a key role against susceptibility to and severity of TLE.
|
29363864 |
2018 |
|
Mental Depression
|
|
0.010 |
GeneticVariation
|
BEFREE |
Logistic regression analysis revealed a marginally significant interaction (genetic variant × SLE) at rs4523957 (P uncorrected = 0.0034) with depression and a significant association of single nucleotide polymorphism identified from evidence of BD GWAS (rs7296288, downstream of DHH at 12q13.1) with depression as the main effect (P uncorrected = 9.4 × 10(-4), P corrected = 0.0424).
|
25517604 |
2014 |
|
Depressive disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Logistic regression analysis revealed a marginally significant interaction (genetic variant × SLE) at rs4523957 (P uncorrected = 0.0034) with depression and a significant association of single nucleotide polymorphism identified from evidence of BD GWAS (rs7296288, downstream of DHH at 12q13.1) with depression as the main effect (P uncorrected = 9.4 × 10(-4), P corrected = 0.0424).
|
25517604 |
2014 |
|
Bipolar Disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Logistic regression analysis revealed a marginally significant interaction (genetic variant × SLE) at rs4523957 (P uncorrected = 0.0034) with depression and a significant association of single nucleotide polymorphism identified from evidence of BD GWAS (rs7296288, downstream of DHH at 12q13.1) with depression as the main effect (P uncorrected = 9.4 × 10(-4), P corrected = 0.0424).
|
25517604 |
2014 |
|
Depressed mood
|
|
0.010 |
GeneticVariation
|
BEFREE |
Logistic regression analysis revealed a marginally significant interaction (genetic variant × SLE) at rs4523957 (P uncorrected = 0.0034) with depression and a significant association of single nucleotide polymorphism identified from evidence of BD GWAS (rs7296288, downstream of DHH at 12q13.1) with depression as the main effect (P uncorrected = 9.4 × 10(-4), P corrected = 0.0424).
|
25517604 |
2014 |