|
Dengue Fever
|
|
0.070 |
GeneticVariation
|
BEFREE |
A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF).
|
29054571 |
2018 |
|
Dengue Fever
|
|
0.070 |
GeneticVariation
|
BEFREE |
Because the -336A/G SNP (rs4804803) polymorphism in the promoter of CD209 modulates DC-SIGN expression, we investigated the putative association of this polymorphism with DENV infection and its pathogenesis.
|
24797508 |
2014 |
|
Dengue Fever
|
|
0.070 |
GeneticVariation
|
BEFREE |
In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos.
|
24911936 |
2014 |
|
Dengue Fever
|
|
0.070 |
GeneticVariation
|
BEFREE |
Polymorphisms in the promoter region of CD209 gene (rs735239, rs4804803, rs2287886) were investigated in 112 hospitalized cases of dengue (DEN) and 104 healthy controls to find out whether they are associated with dengue in a Western Indian population.
|
23624202 |
2013 |
|
Dengue Fever
|
|
0.070 |
GeneticVariation
|
BEFREE |
Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene.
|
22061615 |
2012 |
|
Dengue Fever
|
|
0.070 |
GeneticVariation
|
BEFREE |
the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF.
|
21245921 |
2011 |
|
Dengue Fever
|
|
0.070 |
GeneticVariation
|
BEFREE |
A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever.
|
20470843 |
2010 |
|
Severe Dengue
|
|
0.040 |
GeneticVariation
|
BEFREE |
The overall meta-analysis revealed significant associations between rs4804803 and severe dengue under the recession (<i>GG</i> versus <i>GA/AA</i>: OR = 0.44, 95%CI, 0.23-0.82) and a codominant model (<i>GG</i> versus <i>AA</i>: OR = 0.43, 95%CI, 0.23-0.81), but sensitivity analysis indicated that the significant pooled ORs were not robust.
|
31027310 |
2019 |
|
Severe Dengue
|
|
0.040 |
GeneticVariation
|
BEFREE |
A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF).
|
29054571 |
2018 |
|
Severe Dengue
|
|
0.040 |
GeneticVariation
|
BEFREE |
The rs1800629 A-allele in the TNF gene was associated with an increased risk of DHF (OR = 3.4, CI = 1.235-9.284 p = 0.0212) whereas SNPs rs4804803, rs2780831, rs1801274, rs231775, rs12979860, and rs8099917 showed no association in this cohort.
|
29130827 |
2018 |
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
We screened 4 single nucleotide polymorphisms (SNPs) in the promoter region of CD209, namely -939G>A (rs735240), -871A>G (rs735239), -336A>G (rs4804803) and -139G>A (rs2287886) and tandem repeat polymorphisms in exon 4 of CD209 and CD209L genes looking for association with TB in a Northeastern Brazilian population (295 subjects, 131 TB patients and 164 healthy controls).
|
24874302 |
2014 |
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
The primary objective of this study was to investigate this issue in the model of Mycobacterium tuberculosis and human DC-SIGN encoding CD209 promoter SNP (rs4804803) in Russian Siberian population.
|
22027159 |
2012 |
|
Severe Dengue
|
|
0.040 |
GeneticVariation
|
BEFREE |
the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF.
|
21245921 |
2011 |
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever.
|
20470843 |
2010 |
|
Tuberculosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
A total of 2,176 individuals enrolled in tuberculosis case-control studies from four sub-Saharan Africa countries were genotyped for the CD209 -336A/G SNP (rs4804803).
|
18167547 |
2008 |
|
Virus Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
Among significant associations found between virus infections and genetic variants, we report for the first time an association of rs4804803 (CD209) A and G variants with susceptibility to HBV infection and spontaneous clearance (p<0.001, OR=3.53, 95% CI 2.155; 5.908, and p<0.001, OR=7.75, 95% CI 4.646-13.114, respectively).
|
24797387 |
2014 |
|
Virus Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene.
|
22061615 |
2012 |
|
Hepatitis C
|
|
0.020 |
GeneticVariation
|
BEFREE |
Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene.
|
22061615 |
2012 |
|
Hepatitis C
|
|
0.020 |
GeneticVariation
|
BEFREE |
We conclude that rs4804803, an SNP in the CD209 promoter, contributes to severity of liver disease in chronic HCV infection.
|
20470843 |
2010 |
|
Paracoccidioidomycosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the VDR (rs7975232), the CC genotype (P < 0.001, OR = 5.94, 95% CI = 2.07-17.05), and the C allele (P = 0.027, OR = 2.71, 95% CI = 1.07-6.86), as well as the GG genotype in DC-SIGN (rs4804803) (P = 0.032, OR: 3.76, 95%, I = 1.06-13.38) are associated with an increased risk of oral PCM.
|
30367528 |
2019 |
|
Recession
|
|
0.010 |
GeneticVariation
|
BEFREE |
The overall meta-analysis revealed significant associations between rs4804803 and severe dengue under the recession (<i>GG</i> versus <i>GA/AA</i>: OR = 0.44, 95%CI, 0.23-0.82) and a codominant model (<i>GG</i> versus <i>AA</i>: OR = 0.43, 95%CI, 0.23-0.81), but sensitivity analysis indicated that the significant pooled ORs were not robust.
|
31027310 |
2019 |
|
Nasopharyngeal carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
At rs4804803, risk of NPC was significantly higher in individuals with the genotype GG than in those with the genotype AA (adjusted OR 9.038, 95%CI 1.708-47.822).
|
28694559 |
2017 |
|
Chikungunya Fever
|
|
0.010 |
GeneticVariation
|
BEFREE |
The frequency of CD209 gene G/G genotype of rs4804803 was significantly higher in CHIKV patients compared to healthy controls (p = 0.046).
|
26398832 |
2016 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that the allele G and genotypes G/G and A/G of SNP-871 (rs735239), as well as the alleles G-G (rs735239-rs4804803) and genotypes combined AA-GG (rs735239-rs4804803) were associated with protection of T1DM development.
|
25092567 |
2014 |
|
Tuberculosis, Pulmonary
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our data suggest that CD209 rs4804803 polymorphism increased the risk of PTB in a sample of Iranian population.
|
23751770 |
2014 |