cervical cancer
|
|
0.010 |
GeneticVariation
|
BEFREE |
The preliminary report revealed that the SNP rs4846048 of MTHFR enhanced the risk of CC through association with miR-522, which further regulated cell viability and apoptosis in Hela cells.
|
31750632 |
2020 |
Malignant tumor of cervix
|
|
0.010 |
GeneticVariation
|
BEFREE |
The preliminary report revealed that the SNP rs4846048 of MTHFR enhanced the risk of CC through association with miR-522, which further regulated cell viability and apoptosis in Hela cells.
|
31750632 |
2020 |
Cervix carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The preliminary report revealed that the SNP rs4846048 of MTHFR enhanced the risk of CC through association with miR-522, which further regulated cell viability and apoptosis in Hela cells.
|
31750632 |
2020 |
Carcinoma breast stage IV
|
|
0.010 |
GeneticVariation
|
BEFREE |
We have identified four potentially useful pharmacogenetic markers, TYMS rs2606241, TYMS rs2853741, MTHFR rs3737964, and MTHFR rs4846048 to predict capecitabine-induced HFS in MBC patients.
|
31601265 |
2019 |
Hyalinosis, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
We have identified four potentially useful pharmacogenetic markers, TYMS rs2606241, TYMS rs2853741, MTHFR rs3737964, and MTHFR rs4846048 to predict capecitabine-induced HFS in MBC patients.
|
31601265 |
2019 |
Ischemic stroke
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated four single nucleotide polymorphisms in the MTHFR 3'-UTR [2572 C > A (rs4846049), 4869 C > G (rs1537514), 5488 C > T (rs3737967), and 6685 T > C (rs4846048)] to elucidate associations between ischemic stroke prevalence and prognosis.
|
28963520 |
2017 |
Breast Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype analysis also showed that MTHFR CACCAA and AGTCAC haplotypes (rs12121543-rs13306553-rs9651118-rs1801133-rs4846048-rs1801131) had significant reduced risk of breast cancer (adjusted OR = 0.70, 95 % CI 0.58-0.86; adjusted OR = 0.57, 95 % CI 0.40-0.80) compared with CATTAA haplotype.
|
25566964 |
2015 |
Malignant neoplasm of breast
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype analysis also showed that MTHFR CACCAA and AGTCAC haplotypes (rs12121543-rs13306553-rs9651118-rs1801133-rs4846048-rs1801131) had significant reduced risk of breast cancer (adjusted OR = 0.70, 95 % CI 0.58-0.86; adjusted OR = 0.57, 95 % CI 0.40-0.80) compared with CATTAA haplotype.
|
25566964 |
2015 |
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to investigate the association of four MTHFR polymorphisms, 2572C>A [rs4846049], 4869C>G [rs1537514], 5488C>T [rs3737967], and 6685T>C [rs4846048] with colorectal cancer (CRC) in Koreans.
|
26046315 |
2015 |
Squamous cell carcinoma of esophagus
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our findings suggests that MTHFR rs1801133 C>T, rs4845882 G>A and rs4846048 A>G SNPs may be genetic modifiers for developing ESCC </span>in Chinese Han population.
|
24687778 |
2014 |