rs4968451, BRIP1

N. diseases: 13
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Adult Meningioma
CUI: C0278877
Disease: Adult Meningioma
0.020 GeneticVariation BEFREE The polymorphisms rs4968451T>G in BRIP1 were significantly associated with the risk of meningioma (TT vs. TG vs. GG additive, P = 0.005; TT+TG vs. GG dominant, P = 0.015; TT/GT+GG recessive, P = 0.034). 29581016 2018
Meningioma
CUI: C0025286
Disease: Meningioma
0.020 GeneticVariation BEFREE The polymorphisms rs4968451T>G in BRIP1 were significantly associated with the risk of meningioma (TT vs. TG vs. GG additive, P = 0.005; TT+TG vs. GG dominant, P = 0.015; TT/GT+GG recessive, P = 0.034). 29581016 2018
Meningioma, benign, no ICD-O subtype
0.020 GeneticVariation BEFREE The polymorphisms rs4968451T>G in BRIP1 were significantly associated with the risk of meningioma (TT vs. TG vs. GG additive, P = 0.005; TT+TG vs. GG dominant, P = 0.015; TT/GT+GG recessive, P = 0.034). 29581016 2018
Meningioma, benign, no ICD-O subtype
0.020 GeneticVariation BEFREE We have identified a novel association between rs4968451 and meningioma risk. 18270339 2008
Adult Meningioma
CUI: C0278877
Disease: Adult Meningioma
0.020 GeneticVariation BEFREE We have identified a novel association between rs4968451 and meningioma risk. 18270339 2008
Meningioma
CUI: C0025286
Disease: Meningioma
0.020 GeneticVariation BEFREE We have identified a novel association between rs4968451 and meningioma risk. 18270339 2008
Grade I Meningioma
CUI: C1512260
Disease: Grade I Meningioma
0.010 GeneticVariation BEFREE BRIP1 rs4968451T>G was associated with markedly grade I meningioma risk (TT+TG vs. GG dominant, P = 0.008; TT/GT+GG recessive, P = 0.020). 29581016 2018
Adult Grade I Meningioma
CUI: C2347751
Disease: Adult Grade I Meningioma
0.010 GeneticVariation BEFREE BRIP1 rs4968451T>G was associated with markedly grade I meningioma risk (TT+TG vs. GG dominant, P = 0.008; TT/GT+GG recessive, P = 0.020). 29581016 2018
Childhood Grade I Meningioma
CUI: C2347760
Disease: Childhood Grade I Meningioma
0.010 GeneticVariation BEFREE BRIP1 rs4968451T>G was associated with markedly grade I meningioma risk (TT+TG vs. GG dominant, P = 0.008; TT/GT+GG recessive, P = 0.020). 29581016 2018
Neoplasms
CUI: C0027651
Disease: Neoplasms
0.010 GeneticVariation BEFREE Through genotype-phenotype analysis, the genotype of BRIP1 rs4968451T>G was also strongly associated with tumor-related phenotypes, including the tumor grade and tumor subtypes. 29581016 2018
Transitional Meningioma
CUI: C0334611
Disease: Transitional Meningioma
0.010 GeneticVariation BEFREE In addition, BRIP1 rs4968451T>G was associated with markedly meningothelial and transitional meningioma risk. 29581016 2018
Cervix carcinoma
CUI: C0302592
Disease: Cervix carcinoma
0.010 GeneticVariation BEFREE The results showed that rs16945692 (intron 1), rs4968451 (intron 4), rs4986764 (exon 18) and rs7213430 (3'UTR) were significantly associated with cervical cancer (P<0.05). 23644138 2013
Malignant tumor of cervix
CUI: C0007847
Disease: Malignant tumor of cervix
0.010 GeneticVariation BEFREE The results showed that rs16945692 (intron 1), rs4968451 (intron 4), rs4986764 (exon 18) and rs7213430 (3'UTR) were significantly associated with cervical cancer (P<0.05). 23644138 2013
cervical cancer
CUI: C4048328
Disease: cervical cancer
0.010 GeneticVariation BEFREE The results showed that rs16945692 (intron 1), rs4968451 (intron 4), rs4986764 (exon 18) and rs7213430 (3'UTR) were significantly associated with cervical cancer (P<0.05). 23644138 2013
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.010 GeneticVariation BEFREE The SNP rs4968451, which maps to intron 4 of the gene that encodes breast cancer susceptibility gene 1-interacting protein 1, was consistently associated with an increased risk of developing meningioma. 18270339 2008
Malignant neoplasm of breast
CUI: C0006142
Disease: Malignant neoplasm of breast
0.010 GeneticVariation BEFREE The SNP rs4968451, which maps to intron 4 of the gene that encodes breast cancer susceptibility gene 1-interacting protein 1, was consistently associated with an increased risk of developing meningioma. 18270339 2008