|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
The results of our meta-analysis suggest that SELE genetic polymorphisms might be strongly correlated with an increased risk of CHD (allele model: OR 2.08, 95% CI 1.67-2.58, P<0.001; dominant model: OR 2.12, 95% CI 1.68-2.68, P<0.001; respectively), especially the SELE 554L/F, 98G/T and 128S/R polymorphisms.
|
24458828 |
2014 |
|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
The interaction of classical risk factors for CAD with S128R polymorphism in our study population showed that the significant determinants of coronary artery disease were presence of diabetes, hypertension, smoking habit, elevated serum triglycerides and low HDL.
|
19942746 |
2009 |
|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
The interactive role of type 2 diabetes mellitus and E-selectin S128R mutation on susceptibility to coronary heart disease.
|
17578587 |
2007 |
|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
E-selectin S128R polymorphism and severe coronary artery disease in Arabs.
|
16756647 |
2006 |
|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
Association between the Ser128Arg variant of the E-selectin and risk of coronary artery disease in the central China.
|
16061120 |
2005 |
|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
An association between the Ser128 Arg polymorphism and coronary heart disease (CHD) has been previously demonstrated in a white population.
|
15871853 |
2005 |
|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
In subjects suffering from diabetes mellitus type 2 the E-selectin S128R polymorphism is not associated with coronary artery disease nor with an increased risk for myocardial infarction.
|
15013273 |
2003 |
|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
All P-selectin polymorphisms as well as a common E-selectin polymorphism, Ser128Arg which has been reported as being associated with an increased risk of premature coronary heart disease (CHD), and is in tight linkage disequilibrium with several P-selectin polymorphisms, were investigated in 647 patients with MI and 758 control subjects from four regions of France and Northern Ireland (the ECTIM study).
|
9668170 |
1998 |
|
Coronary heart disease
|
|
0.090 |
GeneticVariation
|
BEFREE |
We found a correlation between the M235T molecular variant of AGT and the S128R variant of E-selectin to early severe CHD.
|
9020385 |
1997 |
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
Statistically significant results found for the various QTs and SNPs were: rs3774933, rs230528, rs230521, rs1005819 and rs1609798 (intronic, NFKB1) with APOB; rs5361 (Missense, R greatr than S, SELE) and rs4648004 (Intronic, NFKB1) with FBG; rs4220 (Missense, K greater than R, FGB) with HCY; and rs3025035 (Intronic, VEGFA) with CHOL-H. SNPs in SELE, VEGFA, FGB and NFKB1 genes impact significantly on levels of quantitative precursors of CAD in Marwaris.
|
22116284 |
2011 |
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
The interaction of classical risk factors for CAD with S128R polymorphism in our study population showed that the significant determinants of coronary artery disease were presence of diabetes, hypertension, smoking habit, elevated serum triglycerides and low HDL.
|
19942746 |
2009 |
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
In the present study, we assessed the possible interactive effect of DM2 and E-selectin S128R polymorphism with respect to its predisposing individuals to CAD, using as a study model a population of 1,112 patients and 427 angiographed controls of Saudi origin.
|
17578587 |
2007 |
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
Among the Saudi population, The E-selectin p. S128R (g. A561C) polymorphism was associated with angiographic CAD in Univariate analysis, but lost its association in multivariate analysis.
|
16756647 |
2006 |
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
Association between the Ser128Arg variant of the E-selectin and risk of coronary artery disease in the central China.
|
16061120 |
2005 |
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
In subjects suffering from diabetes mellitus type 2 the E-selectin S128R polymorphism is not associated with coronary artery disease nor with an increased risk for myocardial infarction.
|
15013273 |
2003 |
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
The Ser128Arg polymorphism of E-selectin was analyzed in 101 (derivation) and 92 (validation) CAD patients.
|
12036529 |
2002 |
|
Coronary Artery Disease
|
|
0.080 |
GeneticVariation
|
BEFREE |
After controlling for other CAD risk factors (plasma total cholesterol, triglyceride, LDL-apolipoprotein B. cigarette smoking and the S128R mutation) by multiple logistic analysis, the G98T mutation in the E-selectin gene was still a significant predictor of premature CAD [p = 0.022, odds ratio (95%, CI)= 3.58 (1.20-10.67)].
|
11168027 |
2001 |
|
Arteriosclerosis
|
|
0.070 |
GeneticVariation
|
BEFREE |
The rs1805193, rs5361, and rs5355 single nucleotide polymorphisms in the E-selectin gene (SEL-E) are associated with subclinical atherosclerosis: The Genetics of Atherosclerotic Disease (GEA) Mexican study.
|
30501958 |
2019 |
|
Atherosclerosis
|
|
0.070 |
GeneticVariation
|
BEFREE |
The rs1805193, rs5361, and rs5355 single nucleotide polymorphisms in the E-selectin gene (SEL-E) are associated with subclinical atherosclerosis: The Genetics of Atherosclerotic Disease (GEA) Mexican study.
|
30501958 |
2019 |
|
Atherosclerosis
|
|
0.070 |
GeneticVariation
|
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
|
Arteriosclerosis
|
|
0.070 |
GeneticVariation
|
BEFREE |
Ser 128Arg of E-selectin and the K469E of ICAM-1 polymorphisms may be involved in predisposition to atherosclerosis.
|
22648254 |
2012 |
|
Arteriosclerosis
|
|
0.070 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient populations with atherosclerosis or restenosis.
|
16908800 |
2006 |
|
Atherosclerosis
|
|
0.070 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient populations with atherosclerosis or restenosis.
|
16908800 |
2006 |
|
Atherosclerosis
|
|
0.070 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient groups with atherosclerosis or restenosis.
|
15546947 |
2005 |
|
Arteriosclerosis
|
|
0.070 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient groups with atherosclerosis or restenosis.
|
15546947 |
2005 |