rs563649, OPRM1

N. diseases: 2
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Pain
CUI: C0030193
Disease: Pain
0.020 GeneticVariation BEFREE The relationship of pain complaints and activation in the periaqueductal gray and ventral striatum depended on the T-allele of rs563649. 28092323 2017
Pain
CUI: C0030193
Disease: Pain
0.020 GeneticVariation BEFREE Examination of polymorphisms within the human OPRM1 gene locus identified strong association between single nucleotide polymorphism (SNP) rs563649 and individual variations in pain perception. 19103668 2009
Widespread Chronic Pain
CUI: C3178789
Disease: Widespread Chronic Pain
0.010 GeneticVariation BEFREE Three SNPs forming a proposed "pain-protective" haplotype in GCH1 (rs10483639, rs3783641 and rs8007267) and two SNPs in OPRM1 (rs1777971 (A118G) and rs563649) were genotyped in cases with persistent CWP (CWP present at >or=2 time-points) and controls who were pain-free at all time-points. 19775452 2009