Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Malignant neoplasm of breast
|
0.700 | GeneticVariation | CLINVAR | Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care. | 26786923 | 2016 | |||||
Malignant neoplasm of breast
|
0.700 | GeneticVariation | CLINVAR | Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer. | 26315354 | 2015 | |||||
Neoplastic Syndromes, Hereditary
|
0.700 | GeneticVariation | CLINVAR | Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer. | 26315354 | 2015 | |||||
Neoplastic Syndromes, Hereditary
|
0.700 | GeneticVariation | CLINVAR | Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls. | 26283626 | 2015 | |||||
Malignant neoplasm of breast
|
0.700 | GeneticVariation | CLINVAR | Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease. | 24556621 | 2014 | |||||
Neoplastic Syndromes, Hereditary
|
0.700 | GeneticVariation | CLINVAR | Breast-cancer risk in families with mutations in PALB2. | 25099575 | 2014 | |||||
Neoplastic Syndromes, Hereditary
|
0.700 | GeneticVariation | CLINVAR | Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada. | 25225577 | 2014 | |||||
Neoplastic Syndromes, Hereditary
|
0.700 | GeneticVariation | CLINVAR | Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease. | 24556621 | 2014 | |||||
Malignant neoplasm of breast
|
0.700 | GeneticVariation | CLINVAR | PALB2: the hub of a network of tumor suppressors involved in DNA damage responses. | 24998779 | 2014 | |||||
Malignant neoplasm of breast
|
0.700 | GeneticVariation | CLINVAR | Breast-cancer risk in families with mutations in PALB2. | 25099575 | 2014 | |||||
Malignant neoplasm of breast
|
0.700 | GeneticVariation | CLINVAR | Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada. | 25225577 | 2014 | |||||
Neoplastic Syndromes, Hereditary
|
0.700 | GeneticVariation | CLINVAR | Structural basis for recruitment of BRCA2 by PALB2. | 19609323 | 2009 | |||||
Malignant neoplasm of breast
|
0.700 | GeneticVariation | CLINVAR | PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. | 19584259 | 2009 | |||||
Malignant neoplasm of breast
|
0.700 | GeneticVariation | CLINVAR | PALB2 regulates recombinational repair through chromatin association and oligomerization. | 19423707 | 2009 |