rs587778556, NFE2L2

N. diseases: 2
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Tauopathies
CUI: C0949664
Disease: Tauopathies
0.020 GeneticVariation BEFREE In this study, we examined whether BFT confers neuroprotection against tau phosphorylation and the generation of neurofibrillary tangles (NFTs) in the P301S mouse model of tauopathy. 29860433 2018
Tauopathies
CUI: C0949664
Disease: Tauopathies
0.020 GeneticVariation BEFREE The present study examined the effects of MB in the P301S mouse model of tauopathy. 24556215 2014
Neurodegenerative Disorders
CUI: C0524851
Disease: Neurodegenerative Disorders
0.010 GeneticVariation BEFREE The activation of Nrf2/ARE genes is neuroprotective in other transgenic mouse models of neurodegenerative diseases and it appears to be an important mediator of the neuroprotective effects of MB in P301S mice. 24556215 2014