Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Genomic analysis of inherited breast cancer among Palestinian women: Genetic heterogeneity and a founder mutation in TP53.
|
28486781 |
2017 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Recurrent TP53 missense mutation in cancer patients of Arab descent.
|
27866339 |
2017 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study.
|
27501770 |
2016 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Increased oxidative metabolism in the Li-Fraumeni syndrome.
|
23484829 |
2013 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma.
|
23175693 |
2013 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
|
21343334 |
2011 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Radio-induced malignancies after breast cancer postoperative radiotherapy in patients with Li-Fraumeni syndrome.
|
21059199 |
2010 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation.
|
20128691 |
2010 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis.
|
20471942 |
2010 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Transcriptional functionality of germ line p53 mutants influences cancer phenotype.
|
17606709 |
2007 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Characterization of the p53 mutants ability to inhibit p73 beta transactivation using a yeast-based functional assay.
|
12917626 |
2003 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis.
|
12826609 |
2003 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Tumour p53 mutations exhibit promoter selective dominance over wild type p53.
|
11896595 |
2002 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.
|
11429705 |
2001 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Screening for germ line TP53 mutations in breast cancer patients.
|
1591732 |
1992 |
Li-Fraumeni Syndrome
|
|
0.800 |
CausalMutation
|
CLINVAR |
Inherited p53 gene mutations in breast cancer.
|
1581912 |
1992 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Recurrent TP53 missense mutation in cancer patients of Arab descent.
|
27866339 |
2017 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Genomic analysis of inherited breast cancer among Palestinian women: Genetic heterogeneity and a founder mutation in TP53.
|
28486781 |
2017 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study.
|
27501770 |
2016 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Increased oxidative metabolism in the Li-Fraumeni syndrome.
|
23484829 |
2013 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
|
21343334 |
2011 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation.
|
20128691 |
2010 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Radio-induced malignancies after breast cancer postoperative radiotherapy in patients with Li-Fraumeni syndrome.
|
21059199 |
2010 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Transcriptional functionality of germ line p53 mutants influences cancer phenotype.
|
17606709 |
2007 |
Neoplastic Syndromes, Hereditary
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Screening for germ line TP53 mutations in breast cancer patients.
|
1591732 |
1992 |