rs63751264, MAPT

N. diseases: 2
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Pick Disease of the Brain
CUI: C0236642
Disease: Pick Disease of the Brain
0.810 GeneticVariation BEFREE Taken together, results indicate that the K369I mutation in Tau can cause a dementing disease with a neuropathology like that of Pick's disease. 11601501 2001
Pick Disease of the Brain
CUI: C0236642
Disease: Pick Disease of the Brain
0.810 CausalMutation CLINVAR
Pick Disease of the Brain
CUI: C0236642
Disease: Pick Disease of the Brain
0.810 GeneticVariation UNIPROT
Frontotemporal dementia
CUI: C0338451
Disease: Frontotemporal dementia
0.010 GeneticVariation BEFREE K3 mice develop a progressive histopathology that is reminiscent of that in human FTD with the K369I mutation. 18832465 2008